Description

2-(Acetylamino)-3-[(4-Bromophenyl)Sulfanyl]Propanoic Acid is a specialized sulfur-containing amino acid derivative that serves as a critical building block in advanced organic synthesis. This compound is valued for its unique molecular architecture, which incorporates both a bromophenyl sulfide moiety and an acetyl-protected amino acid functionality, enabling precise chemical modifications. It is primarily sought by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, including the development of enzyme inhibitors and novel bioactive molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting enzymes or receptors where the bromophenyl sulfide group is essential for binding.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and the development of protease or kinase inhibitors.
• Agrochemical Synthesis: Serves as a building block for creating new active ingredients in crop protection products, leveraging its halogen and sulfur components.
• Peptidomimetics Development: Employed in the design and synthesis of peptide analogs and mimetics to enhance metabolic stability and bioavailability.
• Chemical Biology Probes: Utilized in the creation of labeled compounds or affinity probes for studying biological pathways and target identification.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific, multi-step synthetic projects.

Basic Information

Product Name	2-(Acetylamino)-3-[(4-Bromophenyl)Sulfanyl]Propanoic Acid
CAS No.	126253-78-9
Molecular Formula	C11H12BrNO3S
Molecular Weight	318.19 g/mol
Synonyms	N-Acetyl-3-[(4-bromophenyl)thio]alanine; 3-[(4-Bromophenyl)thio]-N-acetylalanine; 2-Acetamido-3-(4-bromophenylthio)propanoic acid; N-Acetyl-3-(4-bromophenylthio)alanine; Alanine, N-acetyl-3-[(4-bromophenyl)thio]-; (2R/S)-2-Acetamido-3-[(4-bromophenyl)sulfanyl]propanoic acid (racemic mixture); 2-(Acetylamino)-3-[(4-bromophenyl)thio]propionic Acid
EINECS	Contact for details

Quality Control

Our 2-(Acetylamino)-3-[(4-Bromophenyl)Sulfanyl]Propanoic Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.