Description

Cd4 (81-92) is a synthetic peptide fragment corresponding to a specific region of the CD4 protein, a critical receptor on T-helper cells. This high-purity compound is essential for advanced immunological research and pharmaceutical development, particularly in studying T-cell activation and HIV entry mechanisms. It serves as a vital tool for researchers in biotechnology, immunology, and virology, as well as for developers of novel therapeutics and diagnostic assays targeting the CD4 pathway.

Application

• Biomedical Research: Used as a key reagent in studying T-cell receptor signaling, immune synapse formation, and antigen presentation processes.
• HIV/AIDS Research: Serves as a critical component in assays designed to investigate HIV-1 gp120 binding and viral entry inhibition mechanisms.
• Therapeutic Development: Acts as a reference standard or a starting material in the development of peptide-based immunotherapies and vaccine candidates.
• Diagnostic Assay Production: Employed in the development and calibration of ELISA kits and other immunoassays for detecting CD4-related immune responses.
• Structure-Activity Relationship (SAR) Studies: Utilized to map critical binding domains and interactions between CD4 and its ligands, such as MHC class II molecules.
• Cell Culture & In Vitro Studies: Applied in cell-based assays to modulate CD4-mediated signaling pathways and study downstream cellular effects.

Basic Information

Product Name	Cd4 (81-92)
CAS No.	126144-46-5
Molecular Formula	C58H94N18O18
Molecular Weight	1307.5 g/mol
Synonyms	CD4 (81-92) Peptide; T Cell Surface Glycoprotein CD4 (81-92); CD4 Fragment (81-92); Human CD4(81-92); CD4 Peptide Residues 81-92; L-Leucine, L-lysyl-L-phenylalanyl-L-valyl-L-threonyl-L-tryptophyl-L-lysyl-L-threonyl-L-arginyl-L-leucyl-L-arginyl-; H-Lys-Phe-Val-Thr-Trp-Lys-Thr-Arg-Leu-Arg-OH
EINECS	Contact for details

Quality Control

Our Cd4 (81-92) is manufactured under strict quality systems to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and other critical parameters. We adhere to industry-standard quality practices to support your R&D and pre-clinical development needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Peptide Content	≥ 70%
Single Impurity (HPLC)	≤ 1.0%
Amino Acid Analysis	± 10% of theoretical
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.