Description

4-(Pentafluorophenoxy)Piperidine is a high-value, fluorinated piperidine derivative that serves as a critical building block in advanced organic synthesis. This compound matters for its unique chemical structure, which combines a pentafluorophenoxy group with a piperidine ring, offering specific electronic and steric properties for creating novel molecules. Pharmaceutical, agrochemical, and material science R&D teams need it for developing new active ingredients, ligands, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) targets and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides where the fluorinated aromatic moiety enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Acts as a precursor for sophisticated ligands in asymmetric catalysis and transition metal complexes.
• Material Science Research: Building block for specialty polymers, liquid crystals, and advanced organic frameworks (MOFs/COFs) requiring fluorinated components.
• Chemical Biology Probes: Utilized in the design of molecular probes and tags for studying biological systems and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs and research institutions for bespoke synthetic routes and scale-up projects.

Basic Information

Product Name	4-(Pentafluorophenoxy)Piperidine
CAS No.	126120-37-4
Molecular Formula	C11H10F5NO
Molecular Weight	267.20 g/mol
Synonyms	4-(Pentafluorophenoxy)piperidine; Piperidine, 4-(pentafluorophenoxy)-; 1-(2,3,4,5,6-Pentafluorophenoxy)piperidine; 4-(Perfluorophenoxy)piperidine; 126120-37-4; Pentafluorophenyl 4-piperidyl ether; 4-Piperidinol, 1-(pentafluorophenyl) ether
EINECS	Contact for details

Quality Control

Our 4-(Pentafluorophenoxy)Piperidine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We support compliance with relevant guidelines for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.