Description

Sar-Arg-Val-Tyr-Ile-His-Pro-Nh2 is a synthetic heptapeptide amide, a sequence derived from the renin substrate angiotensinogen. This compound is of significant interest in biochemical and pharmacological research, particularly for studying the renin-angiotensin system (RAS) and related enzyme kinetics. It serves as a critical substrate or intermediate for researchers and manufacturers in the fields of cardiovascular research, peptide chemistry, and diagnostic assay development. The product is supplied under stringent quality control to ensure batch-to-batch consistency for reliable experimental results.

Application

• Biochemical Research: Used as a specific substrate for studying the activity and inhibition of renin and other aspartic proteases.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the development of cardiovascular drugs targeting hypertension.
• Diagnostic Reagents: Employed in the formulation of enzyme-linked immunosorbent assays (ELISAs) and other in vitro diagnostic kits for renin activity measurement.
• Peptide Synthesis: Acts as a building block or a model compound for solid-phase peptide synthesis (SPPS) and structure-activity relationship (SAR) studies.
• Academic & Institutional Labs: Utilized in university and research institute settings for fundamental studies on peptide-protein interactions and metabolic pathways.

Basic Information

Product Name	Sar-Arg-Val-Tyr-Ile-His-Pro-Nh2
CAS No.	126112-22-9
Molecular Formula	C44H66N14O9
Molecular Weight	935.1 g/mol
Synonyms	Sar-Arg-Val-Tyr-Ile-His-Pro-amide; Sar1-Renin Substrate (1-7); N-Acetyl-Sar-Arg-Val-Tyr-Ile-His-Pro-NH2; Heptapeptide Renin Substrate Fragment; Angiotensinogen (1-7) analog; Sar-Arg-Val-Tyr-Ile-His-Pro Amide; Sar1-Angiotensinogen (1-7); [Sar1]-Angiotensin I (1-7) amide
EINECS	Contact for details

Quality Control

Every batch of Sar-Arg-Val-Tyr-Ile-His-Pro-Nh2 is manufactured and analyzed under a strict quality management system. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with high-purity standards for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to guarantee traceability and reliability for your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95.0%
Assay (HPLC)	≥ 97.0%
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.