Description

Acetamide, 2,2,2-Trifluoro-N-(4-Iodophenyl)- is a specialized fluorinated and iodinated aromatic amide building block with the CAS registry number 126063-08-9. This compound is valued for its unique molecular structure, which combines electron-withdrawing trifluoroacetyl and iodophenyl groups, making it a critical intermediate in advanced synthetic chemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for constructing complex molecules, particularly in the development of new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, especially in medicinal chemistry programs targeting enzyme inhibition or receptor modulation.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where its halogenated structure can contribute to biological activity and environmental stability.
• Material Science Research: Serves as a precursor for specialty polymers, liquid crystals, or organic electronic materials due to its aromatic and halogenated components.
• Chemical Biology Probes: Utilized in the synthesis of labeled compounds or molecular probes for biochemical and diagnostic research applications.
• Cross-Coupling Reactions: The iodine substituent makes it a valuable substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to build more complex biaryl systems.

Basic Information

Product Name	Acetamide, 2,2,2-Trifluoro-N-(4-Iodophenyl)-
CAS No.	126063-08-9
Molecular Formula	C8H5F3INO
Molecular Weight	315.03 g/mol
Synonyms	N-(4-Iodophenyl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-(4-iodophenyl)acetamide; 4'-Iodo-2,2,2-trifluoroacetanilide; p-Iodophenyltrifluoroacetamide; TFIA; Trifluoroacet-4-iodoanilide; 2,2,2-Trifluoroacet-4-iodoanilide
EINECS	Contact for details

Quality Control

Our Acetamide, 2,2,2-Trifluoro-N-(4-Iodophenyl)- is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and elemental analysis, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and reducing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.