Description

S-(n-Ethylcarbamoyl)Glutathionemonomethylester is a chemically modified derivative of the essential tripeptide glutathione, designed for enhanced stability and specific reactivity. This compound matters for researchers and manufacturers requiring a protected, activated form of glutathione for advanced biochemical synthesis and pharmaceutical development. It is primarily needed by professionals in the pharmaceutical, biotechnology, and life science research sectors for applications in prodrug synthesis, enzyme studies, and as a key intermediate in targeted therapeutic agents.

Application

• Pharmaceutical Intermediate: Used in the synthesis of novel prodrugs and targeted therapeutic agents, particularly in oncology and neurology research.
• Biochemical Research: Serves as a critical reagent in enzyme inhibition studies and the investigation of glutathione-S-transferase (GST) pathways.
• Peptide Chemistry: Acts as a protected building block for the solid-phase or solution-phase synthesis of complex peptides and protein conjugates.
• Antioxidant Studies: Employed as a model compound to study the delivery and release mechanisms of modified antioxidants in cellular systems.
• Diagnostic Development: Utilized in the development of diagnostic assays and kits that measure glutathione-related enzymatic activity.
• Reference Standard: Functions as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.

Basic Information

Product Name	S-(n-Ethylcarbamoyl)Glutathionemonomethylester
CAS No.	125974-21-2
Molecular Formula	C14H25N4O7S
Molecular Weight	393.44 g/mol
Synonyms	S-(N-Ethylcarbamoyl)glutathione monomethyl ester; Glutathione, S-(N-ethylcarbamoyl)-, monomethyl ester; L-Glutathione, S-(N-ethylcarbamoyl)-, monomethyl ester; S-Carbamoylethylglutathione monomethyl ester; γ-Glu-Cys(S-EtCONH2)-Gly-OMe; (2S)-2-Amino-5-[[(2R)-1-[(carboxymethyl)amino]-3-[(ethylcarbamoyl)sulfanyl]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid methyl ester
EINECS	Contact for details

Quality Control

Our S-(n-Ethylcarbamoyl)Glutathionemonomethylester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and tests for residual solvents and moisture content. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.