Description

Benzeneacetic Acid, α,α,4-Trifluoro-, Methyl Ester is a high-purity fluorinated aromatic ester building block, essential for advanced chemical synthesis. This compound matters as a critical intermediate for introducing the trifluoromethylphenyl moiety, a key structural feature that enhances the metabolic stability and lipophilicity of target molecules. It is primarily needed by pharmaceutical R&D and agrochemical manufacturers for developing new active ingredients, as well as by specialty chemical producers engaged in material science and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and anti-inflammatory drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, where the fluorine atoms contribute to improved biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic compounds used in electronic display technologies and organic light-emitting diodes.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing complex, high-value fluorinated specialty chemicals.
• Polymer Modification: Acts as a monomer or modifier in the synthesis of specialty polymers with tailored properties like chemical resistance and thermal stability.
• Research & Development: Utilized in academic and industrial laboratories for methodological studies in fluorination chemistry and organometallic catalysis.

Basic Information

Product Name	Benzeneacetic Acid, α,α,4-Trifluoro-, Methyl Ester
CAS No.	125923-59-3
Molecular Formula	C10H9F3O2
Molecular Weight	218.17 g/mol
Synonyms	Methyl 2,2,4-Trifluorophenylacetate; 2,2,4-Trifluorophenylacetic Acid Methyl Ester; Methyl (2,2,4-Trifluorophenyl)acetate; α,α,4-Trifluorobenzeneacetic Acid Methyl Ester; (2,2,4-Trifluorophenyl)acetic Acid Methyl Ester; Methyl α,α,4-Trifluorophenylacetate
EINECS	Contact for details

Quality Control

Our Benzeneacetic Acid, α,α,4-Trifluoro-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography and spectroscopy, to ensure it meets the high-purity standards required for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your R&D and production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong bases, strong oxidizing agents, and sources of ignition. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.