Description

Fibronectin Adhesion-Promoting Peptide is a synthetic peptide sequence designed to mimic the cell-binding domain of the fibronectin protein. This compound is crucial for promoting cell adhesion, spreading, and migration in various in vitro cell culture applications. It is an essential research and production tool for scientists and manufacturers in the biotechnology, pharmaceutical development, and biomedical research sectors, particularly for studies involving extracellular matrix interactions.

Application

• Cell Culture Substrate Coating: Used to coat tissue culture plates, flasks, and coverslips to enhance attachment and growth of anchorage-dependent cells, including primary cells and stem cells.
• Biomaterial Functionalization: Incorporated into or coated onto synthetic polymers, hydrogels, and 3D scaffolds to create bioactive surfaces for tissue engineering and regenerative medicine.
• Cell Signaling and Mechanobiology Research: Serves as a defined ligand to study integrin-mediated signaling pathways, focal adhesion formation, and cellular responses to the extracellular matrix.
• Diagnostic Assay Development: Employed in the development of cell-based assays for drug discovery, toxicity screening, and research into cell migration and invasion (e.g., wound healing assays).
• Neuroscience Research: Applied to promote neurite outgrowth and support neuronal cell culture in studies of neural development, repair, and disease models.
• Biochip and Biosensor Fabrication: Used to create patterned bioactive surfaces on chips for advanced cell analysis and biosensing applications.

Basic Information

Product Name	Fibronectin Adhesion-Promoting Peptide
CAS No.	125720-21-0
Molecular Formula	C34H59N11O11
Molecular Weight	773.9 g/mol
Synonyms	Fibronectin Cell-Adhesive Peptide; Arg-Gly-Asp-Ser (RGDS) Peptide; RGD Peptide; RGD Sequence; GRGDS; GRGDS Peptide; Cyclo(-Arg-Gly-Asp-D-Phe-Val-); Fibronectin Fragment (GRGDS)
EINECS	Contact for details

Quality Control

Our Fibronectin Adhesion-Promoting Peptide is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and biological activity. A detailed Certificate of Analysis (COA) is provided, reporting results for assay, purity by HPLC, amino acid analysis, and mass spectrometry. Production adheres to GMP-like guidelines suitable for research and bioprocessing applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. For long-term storage, consider desiccation. The product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Assay (Amino Acid Analysis)	≥ 98%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 70%
Solubility	Soluble in water or aqueous buffer
Biological Activity (Cell Adhesion)	Conforms to reference standard

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.