Description

Boc-N-Me-Arg(Mtr)-OH is a protected arginine derivative, specifically designed for use in solid-phase peptide synthesis (SPPS). This compound is critical for researchers and manufacturers requiring precise control over peptide chain assembly, particularly when incorporating methylated arginine residues. It is primarily utilized by pharmaceutical R&D teams, biotech companies, and fine chemical suppliers engaged in the development of therapeutic peptides and peptidomimetics.

Application

• Solid-Phase Peptide Synthesis (SPPS): As a key building block for the controlled incorporation of N-methyl-arginine into peptide sequences.
• Pharmaceutical Research: For the development of novel peptide-based drug candidates targeting various diseases.
• Bioconjugation: Used in the synthesis of peptide tags and linkers for protein labeling and modification studies.
• Process Development: Serves as a high-purity intermediate in the scale-up and optimization of peptide manufacturing processes.
• Academic Research: A valuable tool in biochemistry and molecular biology labs studying protein-protein interactions and post-translational modifications.

Basic Information

Product Name	Boc-N-Me-Arg(Mtr)-OH
CAS No.	125602-26-8
Molecular Formula	C₂₃H₃₇N₅O₇S
Molecular Weight	527.64 g/mol
Synonyms	N-α-(tert-Butoxycarbonyl)-N-ω-(2,3,5,6-tetramethyl-4-methoxybenzenesulfonyl)-N-δ-methyl-L-arginine; Boc-N-methyl-NG-(Mtr)-L-arginine; Boc-NG-Mtr-N-methyl-L-arginine; tert-Butyl N-methyl-N-[N-[(4-methoxy-2,3,5,6-tetramethylphenyl)sulfonyl]carbamimidoyl]-L-ornithinate; Boc-Me-Arg(Mtr)-OH; (S)-2-((tert-Butoxycarbonyl)(methyl)amino)-5-((N'-(4-methoxy-2,3,5,6-tetramethylphenyl)sulfonyl)carbamimidamido)pentanoic acid
EINECS	Contact for details

Quality Control

Our Boc-N-Me-Arg(Mtr)-OH is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements of peptide synthesis. Certificates of Analysis (COA) with full traceability are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Optical Rotation	-15° to -20° (c=1 in DMF)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.