Description

n-(N'-(2'-Nitrophenyl)Thiocarbamyl)Pyrrolidine-2-Carboxylic Acid is a specialized heterocyclic building block featuring a pyrrolidine carboxylic acid core modified with a thiocarbamyl linkage to a nitrophenyl group. This compound matters as a key intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development where its unique structure enables the creation of novel bioactive compounds. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing peptidomimetics and other nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of potential drug candidates, especially those targeting enzyme inhibition or receptor modulation.
• Peptidomimetic Research: Used to construct non-peptide scaffolds that mimic the structure and function of natural peptides, enhancing metabolic stability.
• Agrochemical Synthesis: Acts as a precursor in the development of novel herbicides or pesticides with specific modes of action.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and protein functions.
• Ligand Development for Catalysis: Employed in creating novel chiral ligands for asymmetric synthesis and catalytic applications.
• Material Science Research: Investigated as a monomer or additive for creating functional polymers with specific chemical properties.

Basic Information

Product Name	n-(N'-(2'-Nitrophenyl)Thiocarbamyl)Pyrrolidine-2-Carboxylic Acid
CAS No.	125421-24-1
Molecular Formula	C₁₂H₁₃N₃O₄S
Molecular Weight	295.31 g/mol
Synonyms	2-Pyrrolidinecarboxylic acid, 1-[[(2-nitrophenyl)amino]thioxomethyl]-; 1-[(2-Nitrophenyl)carbamothioyl]pyrrolidine-2-carboxylic acid; (S)-1-((2-Nitrophenyl)carbamothioyl)pyrrolidine-2-carboxylic acid; N-(2-Nitrophenylcarbamothioyl)proline; L-Proline, N-[(2-nitrophenyl)carbamothioyl]-; Pyrrolidine-2-carboxylic acid, N-(N'-(2'-nitrophenyl)thiocarbamoyl)-; 125421-24-1; ATCC 25100
EINECS	Contact for details

Quality Control

Our n-(N'-(2'-Nitrophenyl)Thiocarbamyl)Pyrrolidine-2-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.