Description

Brain Natriuretic Peptide-45 (BNP-45) is a specific, biologically active peptide fragment derived from the precursor prohormone of B-type natriuretic peptide. This high-purity peptide is critical for research and development in cardiovascular diagnostics and therapeutic discovery. It serves as a vital reference standard and active pharmaceutical ingredient for scientists and manufacturers in the pharmaceutical, biotechnology, and in vitro diagnostics (IVD) industries.

Application

• Reference Standard for Immunoassays: Primary calibration material for BNP and NT-proBNP diagnostic test kits used in clinical laboratories.
• Cardiovascular Research: Used in biochemical and pharmacological studies to investigate heart failure, hypertension, and renal function.
• Therapeutic Agent Development: Serves as a key intermediate or active moiety in the development of novel peptide-based cardiovascular drugs.
• Quality Control Reagent: Employed by IVD kit manufacturers for lot-to-lot consistency testing and assay validation.
• Antibody Production & Characterization: Essential for the immunization process and specificity testing in the development of monoclonal and polyclonal antibodies against BNP.
• Academic & Institutional Research: Used in university and hospital labs for fundamental studies on natriuretic peptide systems and signal transduction pathways.

Basic Information

Product Name	Brain Natriuretic Peptide-45
CAS No.	125387-66-8
Molecular Formula	C204H346N64O64S4
Molecular Weight	4566.3 g/mol
Synonyms	BNP-45; BNP (1-45); B-type Natriuretic Peptide (1-45); Natriuretic Peptide B (1-45); Human BNP-45; Brain Natriuretic Peptide 1-45; BNP Fragment 1-45; hBNP(1-45)
EINECS	Contact for details

Quality Control

Our Brain Natriuretic Peptide-45 is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, MS for identity confirmation, and stringent endotoxin and bioburden controls where applicable. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research and pharmaceutical-grade standards.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 2.0%
Biological Activity	Assayed (Contact for details)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.