Description

(S)-n-(4-Nitro-Phenyl)-L-Alanine CAS NO 125376-35-4 is a high-purity, non-natural amino acid derivative characterized by its chiral (S)-configuration and a para-nitro phenyl substituent. This compound matters as a critical chiral building block and intermediate for the synthesis of more complex molecules in advanced research and development. It is primarily needed by pharmaceutical R&D teams and fine chemical manufacturers for applications in drug discovery, peptide synthesis, and as a precursor for chiral catalysts or ligands.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies.
• Peptide Chemistry: Used in the solid-phase or solution-phase synthesis of modified peptides, incorporating the nitro-phenyl group for specific structural or functional studies.
• Organocatalyst & Ligand Precursor: Serves as a starting material for the development of chiral organocatalysts or metal-complexing ligands used in asymmetric synthesis.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate enzyme mechanisms and inhibition.
• Material Science: Potential monomer or additive in the development of specialized polymers and advanced functional materials.

Basic Information

Product Name	(S)-n-(4-Nitro-Phenyl)-L-Alanine
CAS No.	125376-35-4
Molecular Formula	C9H10N2O4
Molecular Weight	210.19 g/mol
Synonyms	(S)-2-Amino-3-(4-nitrophenyl)propanoic acid; L-4-Nitrophenylalanine; (S)-4-Nitro-L-phenylalanine; (S)-α-Amino-4-nitrobenzenepropanoic acid; 4-Nitro-L-Phe; p-Nitro-L-phenylalanine; (S)-3-(4-Nitrophenyl)alanine; N-(4-Nitrophenyl)-L-alanine
EINECS	Contact for details

Quality Control

Our (S)-n-(4-Nitro-Phenyl)-L-Alanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure compliance with high-purity standards suitable for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.