Description

trans-2-Cyano-1-Cyclohexanol is a versatile chiral building block and intermediate characterized by its cyano and hydroxyl functional groups on a cyclohexane ring. This compound is of significant value in organic synthesis, particularly for the construction of complex molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists in the fine chemical and active pharmaceutical ingredient (API) manufacturing sectors.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging its structural motif for biological activity.
• Ligand and Catalyst Precursor: Serves as a starting material for the preparation of chiral ligands used in asymmetric catalysis.
• Fine Chemical Production: Employed in custom synthesis and the manufacture of specialty chemicals for various high-value applications.
• Academic and Industrial Research: A valuable compound for methodological development in organic chemistry and material science.

Basic Information

Product Name	trans-2-Cyano-1-Cyclohexanol
CAS No.	125291-55-6
Molecular Formula	C7H11NO
Molecular Weight	125.17 g/mol
Synonyms	trans-2-Cyano-1-Cyclohexanol; trans-2-Cyclohexanolcarbonitrile; (1R,2R)-2-Cyano-1-cyclohexanol; (1S,2S)-2-Cyano-1-cyclohexanol; 2-Cyano-1-cyclohexanol (trans-); 1-Cyclohexanol, 2-cyano-, trans-; 2-Cyclohexanolcarbonitrile (trans-); 125291-55-6
EINECS	Contact for details

Quality Control

Our trans-2-Cyano-1-Cyclohexanol is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chromatographic purity and chiral purity assays, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccator to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.