Description

2-(2,4,5-Trifluorophenyl)-4,5-Dihydro-4,4-Dimethyloxazole is a high-value fluorinated heterocyclic building block, specifically an oxazoline derivative, critical for advanced organic synthesis. Its primary commercial value lies in serving as a versatile precursor for the development of active pharmaceutical ingredients (APIs) and agrochemicals, where the trifluorophenyl moiety imparts desirable metabolic stability and bioavailability. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce complex fluorinated architectures into their target molecules.

Application

• Pharmaceutical Intermediate: Key synthon for constructing bioactive molecules, particularly in the synthesis of kinase inhibitors, antiviral agents, and other small-molecule therapeutics.
• Agrochemical Synthesis: Used as a building block for novel herbicides, fungicides, and insecticides, leveraging the fluorine atoms to enhance efficacy and environmental persistence.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and liquid crystals with specific optical or electronic properties.
• Fluorine Chemistry: An important reagent for studying structure-activity relationships (SAR) and introducing fluorinated groups in medicinal chemistry programs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target compounds under cGMP conditions.

Basic Information

Product Name	2-(2,4,5-Trifluorophenyl)-4,5-Dihydro-4,4-Dimethyloxazole
CAS No.	125290-72-4
Molecular Formula	C11H10F3NO
Molecular Weight	229.20 g/mol
Synonyms	4,5-Dihydro-4,4-dimethyl-2-(2,4,5-trifluorophenyl)oxazole; 2-(2,4,5-Trifluorophenyl)-4,4-dimethyl-4,5-dihydrooxazole; 2-(2,4,5-Trifluorophenyl)-4,4-dimethyl-2-oxazoline; 4,4-Dimethyl-2-(2,4,5-trifluorophenyl)-4,5-dihydrooxazole; 2-(2,4,5-Trifluorophenyl)-4,4-dimethyl-4,5-dihydro-1,3-oxazole; Oxazole, 4,5-dihydro-4,4-dimethyl-2-(2,4,5-trifluorophenyl)-
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and commercial use. Each batch is characterized by advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry to confirm identity, purity, and consistency. Certificates of Analysis (COA) are available upon request, detailing all critical quality attributes. We adhere to a quality management system and can support projects requiring material produced under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.