Description

Technetium Tc 99M Mertiatide is a radiopharmaceutical diagnostic agent, a technetium-99m-labeled complex of mercaptoacetyltriglycine (MAG3). This compound is critical for dynamic renal imaging, providing high-quality visualization of renal blood flow, tubular function, and excretion. It is an essential tool for nuclear medicine departments and diagnostic imaging centers, enabling the non-invasive assessment of kidney function and the diagnosis of conditions such as renal artery stenosis and obstructive uropathy.

Application

• Renal Scintigraphy (Renography): Primary agent for dynamic functional imaging of the kidneys to evaluate renal plasma flow and tubular secretion.
• Assessment of Renal Function: Used to quantify split renal function, particularly useful in patients with suspected unilateral renal disease or prior to nephrectomy.
• Diagnosis of Obstructive Uropathy: Helps differentiate between obstructive and non-obstructive hydronephrosis through diuretic-enhanced studies.
• Evaluation of Renal Transplant: Monitors perfusion and function of transplanted kidneys, aiding in the early detection of complications like rejection or vascular thrombosis.
• Pediatric Renal Imaging: Preferred agent for pediatric patients due to its favorable radiation dosimetry and reliable pharmacokinetics.
• Research Applications: Utilized in clinical research studies investigating renal physiology, pharmacokinetics of new drugs, and novel imaging protocols.

Basic Information

Product Name	Technetium Tc 99M Mertiatide
CAS No.	125224-05-7
Molecular Formula	C11H16N4O6S99mTc
Molecular Weight	~ 400.3 g/mol (for 99mTc complex)
Synonyms	Technetium Tc 99m Mertiatide; Tc-99m Mertiatide; 99mTc-MAG3; Mercaptoacetyltriglycine-99mTc; Technetium-99m MAG3; Technescan MAG3; Mertiatide (99mTc); Kit for the preparation of Technetium Tc 99m Mertiatide
EINECS	Contact for details

Quality Control

Every batch of Technetium Tc 99M Mertiatide is manufactured and tested under strict radiopharmaceutical Good Manufacturing Practice (GMP) guidelines. Quality control includes rigorous testing for radiochemical purity, radionuclidic purity, pH, sterility, and apyrogenicity to ensure compliance with international pharmacopeial standards (e.g., USP, Ph. Eur.). A comprehensive Certificate of Analysis (COA) detailing all release specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. The lyophilized kit powder should be stored at 2-8°C. After reconstitution with Sodium Pertechnetate Tc 99m Injection, the prepared radiopharmaceutical should be used within the specified time frame (typically 6-8 hours post-preparation) and must be stored and handled in accordance with local radiation safety regulations.

Specification

Item	Specification
Appearance (Kit)	White to off-white lyophilized powder
Identification (HPLC/TLC)	Complies
Radiochemical Purity (HPLC)	≥ 95.0%
pH (after reconstitution)	5.0 - 7.5
Sterility Test	Sterile
Bacterial Endotoxins	< 175 EU/Vial
Radionuclidic Purity	≥ 99.9% 99mTc

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.