Description

(R)-(-)-3-Hydroxybutyronitrile is a high-value chiral building block and key intermediate in organic synthesis. This optically active compound is essential for the production of enantiomerically pure pharmaceuticals and fine chemicals, where stereochemical control is critical for efficacy and safety. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing advanced active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor for the synthesis of β-blockers, statins, and other active pharmaceutical ingredients (APIs) requiring the (R)-configuration.
• Agrochemical Synthesis: Used in the production of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Serves as a building block for chiral ligands, catalysts, and advanced materials used in asymmetric synthesis.
• Biochemical Research: Employed in metabolic pathway studies and as a precursor for labeled compounds in research and development.
• Flavor and Fragrance Industry: Potential intermediate for the synthesis of specific chiral aroma chemicals.

Basic Information

Product Name	(R)-(-)-3-Hydroxybutyronitrile
CAS No.	125103-95-9
Molecular Formula	C4H7NO
Molecular Weight	85.10 g/mol
Synonyms	(R)-3-Hydroxybutyronitrile; (R)-(-)-3-Hydroxybutanenitrile; (R)-3-Hydroxybutyric acid nitrile; (R)-3-Cyano-1-butanol; (R)-4-Cyano-2-butanol; D-(-)-3-Hydroxybutyronitrile; (R)-Oxybutyronitrile
EINECS	Contact for details

Quality Control

Our (R)-(-)-3-Hydroxybutyronitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing specific parameters such as enantiomeric excess (ee), chemical purity, and identity are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere to maintain stability and purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (ee)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.