Description

Vasotocin, 1-Deamino-Lys(7)-(Fluorescein)-Arg(8)- CAS NO 124924-34-1 is a synthetic, fluorescently labeled analog of the neurohypophysial hormone vasotocin. This compound is engineered for high-affinity binding studies and advanced research applications where precise visualization and tracking are paramount. It is an essential tool for researchers in neuroendocrinology, pharmacology, and cellular biology investigating receptor localization, ligand-receptor interactions, and dynamic cellular processes.

Application

• Receptor Binding and Localization Studies: Used as a fluorescent probe to visualize and quantify vasotocin/vasopressin receptor subtypes (V1a, V1b, V2) in tissue sections, cell cultures, and live-cell imaging.
• Pharmacological Research: Serves as a key tracer in competitive binding assays to evaluate the potency and affinity of novel therapeutic candidates targeting the vasopressin receptor family.
• Cellular Uptake and Trafficking Analysis: Enables real-time tracking of peptide internalization, intracellular trafficking pathways, and metabolic fate within target cells.
• High-Throughput Screening (HTS): Facilitates the development of fluorescence-based assays for drug discovery pipelines focused on cardiovascular, renal, and central nervous system disorders.
• Biomolecular Interaction Analysis: Employed in techniques such as Fluorescence Resonance Energy Transfer (FRET) or Surface Plasmon Resonance (SPR) to study protein-peptide interactions.
• Neuroscience and Behavioral Studies: Aids in mapping the distribution of vasotocinergic pathways in animal models to understand their role in social behavior, stress response, and osmoregulation.

Basic Information

Product Name	Vasotocin, 1-Deamino-Lys(7)-(Fluorescein)-Arg(8)-
CAS No.	124924-34-1
Molecular Formula	C71H91N17O19S2
Molecular Weight	1550.71 g/mol
Synonyms	[1-Deamino,7-Lysine(fluorescein),8-arginine]vasotocin; Fluorescein-Vasotocin; FITC-Vasotocin; Fluorescent Vasotocin; 1-Desamino-8-Arg-vasotocin, 7-Lys(FITC); Arg8-Vasotocin, 1-deamino-7-Lys(Fluorescein)-; Fluorescein-labeled Vasotocin analog; Vasotocin fluorescent conjugate
EINECS	Contact for details

Quality Control

Every batch of our fluorescent peptide analogs is produced and analyzed under stringent quality protocols. We guarantee high purity and batch-to-batch consistency critical for reproducible research outcomes. Quality is verified by multiple orthogonal analytical methods including HPLC, MS, and fluorescence spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, fluorescence characteristics, and functional activity data is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. Aliquot reconstituted solutions to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Yellow to orange lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Fluorescein-to-Peptide Ratio (F/P)	0.8 - 1.2
Extinction Coefficient (ε)	~68,000 cm-1M-1 at 494 nm
Water Content (KF)	≤ 5.0%
Biological Activity	Confirmed by receptor binding assay (Data on COA)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.