Description

Hemoglobin A2 Wrens is a highly purified, standardized reference material derived from human hemoglobin, specifically the A2 variant. This product is critical for the calibration, validation, and quality control of diagnostic assays and research methodologies in clinical chemistry and hematology. It is an essential reagent for laboratories and manufacturers focused on hemoglobinopathy screening, ensuring accurate detection and quantification of Hemoglobin A2 levels, which is vital for diagnosing conditions like β-thalassemia trait.

Application

• Primary standard for the calibration of High-Performance Liquid Chromatography (HPLC) and Capillary Electrophoresis (CE) systems in clinical diagnostics.
• Reference material for the validation and quality control of hemoglobin A2 quantification kits and assays.
• Critical component in the development and manufacturing of in-vitro diagnostic (IVD) devices for hemoglobin variant analysis.
• Essential research tool in biochemical studies of hemoglobin structure, function, and related genetic disorders.
• Used in proficiency testing programs and external quality assessment (EQA) schemes for clinical laboratories.
• Standard for method comparison and harmonization studies across different analytical platforms.

Basic Information

Product Name	Hemoglobin A2 Wrens
CAS No.	124834-70-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Hb A2 Wrens; Hemoglobin A2 (Wrens variant); Hemoglobin variant Wrens; HbA2 Wrens; Hemoglobin A2 Standard (Wrens); Human Hemoglobin A2 Wrens; Thalassemia Reference Standard Wrens; Diagnostic Hemoglobin A2
EINECS	Contact for details

Quality Control

Our Hemoglobin A2 Wrens is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identity confirmation by electrophoresis or chromatography, purity assessment, and stability checks to ensure it meets the exacting standards required for diagnostic and research applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This material is hygroscopic (moisture-sensitive). For long-term stability, store desiccated. Avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	Lyophilized powder
Identification (Electrophoresis/Chromatography)	Conforms to Hemoglobin A2 Wrens profile
Purity (by HPLC)	≥ 95.0%
Solubility	Clear solution in specified buffer
Moisture Content (Karl Fischer)	≤ 5.0%
Hemoglobin Concentration (after reconstitution)	Specified value ± 10%
Stability	Stable for specified period at 2-8°C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.