Description

Potassium Channel-Activating Protein CAS NO 124834-69-1 is a specialized biochemical reagent designed to modulate potassium ion channels, which are critical for regulating cellular excitability and membrane potential. This compound is essential for researchers and developers in life sciences, offering a precise tool for studying cardiovascular, neurological, and metabolic pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and biotechnology companies focused on ion channel-targeted drug discovery and electrophysiology studies.

Application

• Cardiovascular Research: Used as a pharmacological tool to study vasodilation, heart rate regulation, and the role of potassium channels in conditions like hypertension and angina.
• Neuroscience & Neuropharmacology: Critical for investigating neuronal excitability, synaptic transmission, and as a potential lead compound for developing treatments for epilepsy, migraine, and neuropathic pain.
• Metabolic Disorder Studies: Applied in research on insulin secretion, pancreatic β-cell function, and the pathophysiology of diabetes.
• Smooth Muscle Physiology: Employed to examine relaxation mechanisms in bronchial, gastrointestinal, and urogenital tract smooth muscles.
• Drug Discovery & Screening: Serves as a reference standard and active probe in high-throughput screening (HTS) assays for identifying novel potassium channel openers (KCOs).
• Academic & Institutional Research: A key reagent for basic science investigations into ion channel structure, function, and gating mechanisms.

Basic Information

Product Name	Potassium Channel-Activating Protein
CAS No.	124834-69-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Potassium Channel Opener; KATP Channel Activator; Pinacidil-related Protein; Cromakalim Analog; BMS-180448; Potassium Channel Activating Agent; Potassium Channel Stimulating Protein
EINECS	Contact for details

Quality Control

Our Potassium Channel-Activating Protein is manufactured under strict quality management systems to ensure batch-to-batch consistency and reliability for critical research applications. Each lot undergoes comprehensive analytical testing, including purity assay and identity confirmation, to meet the stringent requirements of pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. Due to its hygroscopic (moisture-sensitive) nature, the container must be kept in a dry environment and sealed immediately after use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Biological Activity	Confirmed by functional assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.