Description

n-(4-Iodophenyl)Pregnenolone 3-Carbamate is a chemically modified steroid derivative, specifically a pregnenolone carbamate with an iodophenyl substituent. This compound is of significant interest as a key synthetic intermediate and a potential molecular scaffold in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies engaged in the synthesis of novel steroid-based therapeutics, hormone receptor modulators, and for biochemical studies.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel steroid-based drug candidates.
• Biochemical Research: Used as a probe or reference standard in studies investigating steroid hormone metabolism, receptor binding, and enzyme inhibition.
• Organic Synthesis: Acts as a versatile precursor for further chemical modifications, leveraging the reactivity of the iodine atom for cross-coupling reactions.
• Drug Discovery: Employed in high-throughput screening and medicinal chemistry programs to develop new therapeutic agents targeting endocrine pathways.
• Reference Standard: Utilized in analytical laboratories for method development, calibration, and quality control of related substances.

Basic Information

Product Name	n-(4-Iodophenyl)Pregnenolone 3-Carbamate
CAS No.	124824-12-0
Molecular Formula	C29H36INO3
Molecular Weight	573.51 g/mol
Synonyms	Pregnenolone 3-Carbamate, 21-(4-Iodophenyl)-; 3β-[(Aminocarbonyl)oxy]-21-(4-iodophenyl)pregn-5-en-20-one; 21-(4-Iodophenyl)pregnenolone carbamate; 21-(p-Iodophenyl)pregnenolone 3-carbamate; Pregna-5-en-20-one, 3-[(aminocarbonyl)oxy]-21-(4-iodophenyl)-, (3β)-; 124824-12-0; n-(4-Iodophenyl)Pregnenolone Carbamate
EINECS	Contact for details

Quality Control

Our n-(4-Iodophenyl)Pregnenolone 3-Carbamate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.