Description

Benzamide, 4-Ethynyl-n-Methyl- (9Ci) is a specialized organic compound featuring a benzamide core functionalized with an ethynyl group at the para position and an N-methyl substituent. This unique structure makes it a valuable high-purity building block for advanced chemical synthesis, particularly in pharmaceutical research and material science. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

This compound serves as a versatile intermediate in sophisticated organic synthesis. Key application areas include:

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential active pharmaceutical ingredients (APIs), especially those targeting neurological disorders or cancer.
• Agrochemical Research: Used in developing novel herbicides, fungicides, or plant growth regulators that require a substituted benzamide scaffold.
• Material Science: Acts as a monomer or cross-linking agent in the development of advanced polymers, resins, or conductive materials due to the reactive ethynyl group.
• Chemical Biology & Proteomics: Employed as a tagging reagent or a building block for activity-based probes to study enzyme function and protein interactions.
• Academic & Contract Research: Utilized in universities and CROs for methodological development in synthetic organic chemistry and catalysis studies.

Basic Information

Product Name	Benzamide, 4-Ethynyl-n-Methyl- (9Ci)
CAS No.	124771-44-4
Molecular Formula	C10H9NO
Molecular Weight	159.19 g/mol
Synonyms	4-Ethynyl-N-methylbenzamide; N-Methyl-4-ethynylbenzamide; 4-Ethynyl-N-methyl-benzenecarboxamide; p-Ethynyl-N-methylbenzamide; 4-Ethynylmethylbenzamide; Benzamide, N-methyl-4-ethynyl-; 1-Methyl-3-(4-ethynylphenyl)urea (common misnomer to be corrected); 124771-44-4 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our production of Benzamide, 4-Ethynyl-n-Methyl- (9Ci) adheres to stringent quality protocols. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay, related substances, and residual solvents are provided and can be tailored to meet specific project requirements, including cGMP standards for advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.