Description

Benzene, 1-Fluoro-4-(2-Propynyloxy)- (9Ci) is a specialized fluorinated aromatic building block containing a propargyl ether functional group. This compound is valued for its dual reactivity, serving as a versatile intermediate in advanced organic synthesis and materials science. It is primarily utilized by research and development chemists in the pharmaceutical, agrochemical, and specialty polymer industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS and anti-cancer agents.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced biological activity and metabolic stability.
• Click Chemistry: The propargyl ether moiety makes it an ideal substrate for copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions, facilitating the synthesis of triazole-linked compounds for drug discovery and material science.
• Liquid Crystal & OLED Materials: Serves as a precursor in the synthesis of fluorinated aromatic cores for high-performance electronic and photonic materials, including liquid crystal displays and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorine and alkynyl groups into polymer backbones or side chains, modifying thermal stability, solubility, and surface properties.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions (e.g., Sonogashira, Suzuki) for constructing complex biaryl and conjugated systems.

Basic Information

Item	Details
Product Name	Benzene, 1-Fluoro-4-(2-Propynyloxy)- (9Ci)
CAS No.	124700-26-1
Molecular Formula	C9H7FO
Molecular Weight	150.15 g/mol
Synonyms	1-Fluoro-4-(prop-2-yn-1-yloxy)benzene; 4-Fluorophenyl propargyl ether; p-Fluorophenyl propargyl ether; Propargyl 4-fluorophenyl ether; 4-(2-Propynyloxy)fluorobenzene; 1-Fluoro-4-(2-propynyloxy)benzene; Benzene, 1-fluoro-4-(2-propyn-1-yloxy)-
EINECS	Contact for details

Quality Control

Our Benzene, 1-Fluoro-4-(2-Propynyloxy)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing results from GC, HPLC, NMR, and IR spectroscopy are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C) under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation risk. Keep away from heat, sparks, and open flames. Isolate from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.