Description

(R)-(-)-5-(Trityloxymethyl)-2-Pyrrolidone CAS NO 124665-91-4 is a high-value, chiral pyrrolidone derivative characterized by a trityl-protected hydroxymethyl side chain. This compound serves as a critical chiral building block and advanced intermediate in the synthesis of complex pharmaceutical agents and fine chemicals. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel active ingredients and enantiomerically pure compounds.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the production of enantiomerically pure drugs, particularly in central nervous system (CNS) and antiviral research.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic asymmetric reactions to introduce chirality into target molecules.
• Nootropic & Cognitive Enhancer Research: Serves as a building block in the development of novel pyrrolidone-based nootropic compounds.
• Agrochemical Synthesis: Intermediate for creating chiral active ingredients in herbicides and pesticides.
• Ligand & Catalyst Development: Utilized in the design and synthesis of novel chiral ligands for metal-catalyzed reactions.
• Academic & Process Chemistry: A valuable reagent for methodological studies and scale-up process development in organic chemistry.

Basic Information

Product Name	(R)-(-)-5-(Trityloxymethyl)-2-Pyrrolidone
CAS No.	124665-91-4
Molecular Formula	C24H23NO2
Molecular Weight	357.45 g/mol
Synonyms	(R)-5-(Triphenylmethoxymethyl)-2-pyrrolidinone; (R)-5-(Trityloxymethyl)-2-pyrrolidinone; (5R)-5-[(Triphenylmethoxy)methyl]-2-pyrrolidinone; (R)-NSC 334911; (-)-5-(Trityloxymethyl)-2-pyrrolidone; (R)-(-)-5-(Triphenylmethyloxymethyl)-2-pyrrolidone; (R)-5-[(Triphenylmethoxy)methyl]pyrrolidin-2-one
EINECS	Contact for details

Quality Control

Our (R)-(-)-5-(Trityloxymethyl)-2-Pyrrolidone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with every shipment. We support development and regulatory needs with documentation traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.