Description

Ibuprofen Related Compound (1,3-Dihydroxyprop-2-Yl 2-(4-Isobutylphenyl)Propanonate) is a key chemical reference standard and synthetic intermediate in the pharmaceutical industry. This compound is critical for ensuring the purity, safety, and efficacy of ibuprofen-based drug products through rigorous analytical testing and quality control processes. It is primarily utilized by pharmaceutical manufacturers, analytical laboratories, and research institutions involved in API development, impurity profiling, and regulatory compliance.

Application

• Pharmaceutical Impurity Profiling: Serves as a certified reference standard for the identification and quantification of related substances in ibuprofen active pharmaceutical ingredients (APIs) and finished dosage forms.
• Analytical Method Development & Validation: Used as a critical component in developing and validating HPLC, GC, and other chromatographic methods for ibuprofen analysis.
• Quality Control & Assurance (QC/QA): Essential for in-process testing and release testing of ibuprofen batches to meet pharmacopeial standards (USP, EP, BP).
• Stability Studies: Employed to monitor degradation pathways and establish shelf-life specifications for ibuprofen-containing medications.
• Regulatory Compliance & Documentation: Provides necessary data for regulatory filings (e.g., FDA, EMA) to demonstrate control over potential impurities.
• Chemical Synthesis Research: Acts as a building block or intermediate in advanced organic synthesis for novel anti-inflammatory drug candidates.

Basic Information

Item	Details
Product Name	Ibuprofen Related Compound (1,3-Dihydroxyprop-2-Yl 2-(4-Isobutylphenyl)Propanonate)
CAS No.	124635-85-4
Molecular Formula	C16H22O4
Molecular Weight	278.34 g/mol
Synonyms	1,3-Dihydroxyprop-2-yl 2-(4-isobutylphenyl)propanoate; Ibuprofen 1,3-Dihydroxypropyl Ester; Ibuprofen Propylene Glycol Ester; 2-(4-Isobutylphenyl)propanoic Acid 1,3-Dihydroxy-2-propyl Ester; Ibuprofen Related Compound E (Potential); Ibuprofen Impurity; Propane-1,3-diol, 2-[2-(4-isobutylphenyl)propanoyl]oxy]-
EINECS	Contact for details

Quality Control

Our Ibuprofen Related Compound is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC purity assay, identification by spectroscopic methods (IR, NMR), and control of specific impurities, to ensure it meets the stringent requirements for pharmaceutical reference standards. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.