Description

Lhrh, n-Ac-2-Naphthyl-Ala(1)-4-Chloro-Phe(2)-Pyridyl-Ala(3)-Nicotinyl-Lys(5,6)-Isopropyl-Lys(8)-Alanh2(10)- CAS NO 124361-52-0 is a synthetic, modified peptide analog of Luteinizing Hormone-Releasing Hormone (LHRH). This compound is engineered for enhanced stability and targeted biological activity, making it a critical intermediate in advanced pharmaceutical research and development. It is primarily utilized by research institutions and pharmaceutical companies focused on developing novel therapeutic agents, particularly in the fields of oncology and endocrinology.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of next-generation LHRH antagonist and agonist analogs.
• Endocrine Research: Used in preclinical studies to investigate the modulation of the hypothalamic-pituitary-gonadal axis.
• Oncology R&D: Serves as a precursor in the development of targeted therapies for hormone-dependent cancers, such as prostate and breast cancer.
• Peptide Chemistry Studies: A valuable reference compound for studying structure-activity relationships (SAR) in modified peptide sequences.
• Bioconjugation: The reactive groups present in the structure allow for use in creating peptide-drug conjugates or diagnostic probes.
• Standards & Calibration: Acts as a high-purity analytical standard for quality control in peptide manufacturing.

Basic Information

Item	Detail
Product Name	Lhrh, n-Ac-2-Naphthyl-Ala(1)-4-Chloro-Phe(2)-Pyridyl-Ala(3)-Nicotinyl-Lys(5,6)-Isopropyl-Lys(8)-Alanh2(10)- CAS NO 124361-52-0
CAS No.	124361-52-0
Molecular Formula	C72H94ClN17O13
Molecular Weight	1440.06 g/mol
Synonyms	Ac-2-Nal-4-Cl-Phe-Pyr-Ala-Nic-Lys(iPr)-Lys(iPr)-Ala-NH2; Modified LHRH Antagonist Analog; LHRH Peptide Derivative; Gonadorelin Analog; 5-D-Nicotinoyl-Lys(6)-8-D-iPr-Lys-GnRH; [Ac-2-Nal1, 4-Cl-Phe2, Pyr-Ala3, Nic-Lys5, D-iPr-Lys6, D-iPr-Lys8, Ala10]-LHRH; Cetrorelix-related peptide intermediate
EINECS	Contact for details

Quality Control

Our Lhrh analog is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and MS for identity confirmation, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (MS)	Conforms to theoretical mass
Purity (HPLC)	≥ 95.0%
Single Impurity (HPLC)	≤ 2.0%
Water Content (KF)	≤ 5.0%
Peptide Content	≥ 80.0%
Solubility	Soluble in DMSO, Acetic Acid; Sparingly soluble in water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.