Description

1-(3-Trifluoromethyl-Phenyl)-Cyclopropanecarbonitrile is a versatile and high-value fluorinated organic intermediate. This compound is critical for the synthesis of advanced molecules, particularly in the pharmaceutical and agrochemical sectors, where the introduction of a trifluoromethyl group and a cyclopropane ring can dramatically alter biological activity and metabolic stability. It is primarily sought after by research and development chemists, process development teams, and manufacturers in fine chemical and active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in CNS (Central Nervous System) and oncology research, where the trifluoromethyl moiety enhances lipophilicity and bioavailability.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, leveraging the stability and unique electronic properties of the cyclopropane and trifluoromethyl groups.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in asymmetric catalysis and organometallic chemistry.
• Material Science Research: Employed in the synthesis of fluorinated polymers and advanced organic electronic materials for their specific dielectric and surface properties.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.

Basic Information

Product Name	1-(3-Trifluoromethyl-Phenyl)-Cyclopropanecarbonitrile
CAS No.	124305-68-6
Molecular Formula	C11H8F3N
Molecular Weight	211.18 g/mol
Synonyms	[3-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile; 1-[3-(Trifluoromethyl)phenyl]cyclopropanecarbonitrile; 3-(Cyclopropylcarbonyl)benzotrifluoride; α-Cyano-α-(3-trifluoromethylphenyl)cyclopropane; m-(Trifluoromethyl)phenylcyclopropanecarbonitrile; Cyclopropanecarbonitrile, 1-[3-(trifluoromethyl)phenyl]-; 3-Trifluoromethylphenyl cyclopropanecarbonitrile
EINECS	Contact for details

Quality Control

Our 1-(3-Trifluoromethyl-Phenyl)-Cyclopropanecarbonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring GMP and ISO standards for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.