Description

3-Bromo-5-Cyanobenzyl Bromide is a versatile bifunctional aromatic building block essential for advanced organic synthesis. Its molecular structure, featuring both a reactive benzyl bromide and a cyano group, makes it a critical intermediate for constructing complex molecules with high precision. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, leveraging the bromine and cyano groups for further functionalization.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organocatalysts.
• Material Science Monomer: Acts as a building block for synthesizing specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to create biaryl structures.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.

Basic Information

Product Name	3-Bromo-5-Cyanobenzyl Bromide
CAS No.	124289-24-3
Molecular Formula	C8H5Br2N
Molecular Weight	274.94 g/mol
Synonyms	5-(Bromomethyl)-1,3-dibromobenzonitrile; (3-Bromo-5-cyanophenyl)methyl Bromide; α-Bromo-3-bromo-5-cyanotoluene; 3-Bromo-5-cyanobenzyl Bromide; 1,3-Dibromo-5-(bromomethyl)benzonitrile; 3-Bromo-5-(bromomethyl)benzonitrile; Benzonitrile, 3-bromo-5-(bromomethyl)-
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Cyanobenzyl Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.