Description

1-(2-Bromo-Phenyl)-Cyclopropanecarbonitrile is a versatile and high-purity organic building block characterized by its brominated aromatic and cyclopropane nitrile functional groups. This compound is critical for advanced organic synthesis, enabling the construction of complex molecular architectures in pharmaceutical and agrochemical research. It is primarily sought by R&D chemists and process development scientists in the fine chemical, pharmaceutical intermediate, and material science industries.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials and liquid crystals due to its rigid, conjugated structure.
• Chemical Biology Probes: Utilized as a scaffold for designing molecular probes and inhibitors for biological target identification.
• Custom Synthesis and Contract Manufacturing: A fundamental starting material for custom synthesis projects requiring specific bromo-aryl functionalization.

Basic Information

Product Name	1-(2-Bromo-Phenyl)-Cyclopropanecarbonitrile
CAS No.	124276-75-1
Molecular Formula	C10H8BrN
Molecular Weight	222.08 g/mol
Synonyms	2-Bromobenzylcyclopropanecarbonitrile; (2-Bromophenyl)cyclopropanecarbonitrile; 1-(2-Bromophenyl)cyclopropanecarbonitrile; Cyclopropanecarbonitrile, 1-(2-bromophenyl)-; 2-Bromo-α-(cyclopropylcarbonyl)benzene; 2-Bromophenyl cyclopropanecarbonitrile
EINECS	Contact for details

Quality Control

Our production of 1-(2-Bromo-Phenyl)-Cyclopropanecarbonitrile adheres to stringent in-process controls and final release testing to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing purity, identity, and impurity profiles. Our quality management system is designed to meet the rigorous standards required for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.