Description

6-Hydroxyaldosterone is a significant metabolite of aldosterone, a key mineralocorticoid hormone. This compound is crucial for research into the metabolic pathways and biological activity of aldosterone, particularly in studies related to hypertension, cardiovascular disease, and renal function. It is primarily utilized by pharmaceutical R&D laboratories, clinical research organizations, and academic institutions focused on endocrinology and steroid metabolism.

Application

• Pharmaceutical Reference Standard: Used as a high-purity analytical standard for the quantification of aldosterone metabolites in biological samples via LC-MS or HPLC.
• Endocrinology Research: Critical for investigating the metabolism, clearance, and physiological impact of aldosterone in preclinical studies.
• Diagnostic Kit Development: Serves as a key component in the development and calibration of immunoassays and other diagnostic tests for hormonal disorders.
• Metabolic Pathway Analysis: Employed in studies to map and understand the complete biotransformation pathways of steroid hormones.
• Biomarker Discovery: Aids in the identification and validation of 6-Hydroxyaldosterone as a potential biomarker for specific disease states or drug efficacy.
• Quality Control in Pharma: Used internally by manufacturers for method validation and ensuring the consistency of related steroid-based pharmaceutical products.

Basic Information

Product Name	6-Hydroxyaldosterone
CAS No.	124251-89-4
Molecular Formula	C21H28O6
Molecular Weight	376.45 g/mol
Synonyms	6β-Hydroxyaldosterone; 6-Hydroxy-aldosterone; 11β,21-Dihydroxy-3,20-dioxopregn-4-en-18-al; Aldosterone 6β-hydroxy derivative; 18-Oxo-11β,21-dihydroxy-6β-hydroxypregn-4-ene-3,20-dione
EINECS	Contact for details

Quality Control

Our 6-Hydroxyaldosterone is produced and handled under strict quality management protocols. Each batch is subjected to comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by HPLC, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label or COA. This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.