Description

Pro-Opiomelanocortin Human Joining Peptide(77-109) is a specific bioactive peptide fragment derived from the pro-opiomelanocortin (POMC) precursor protein. This compound is of significant interest in advanced biochemical research and pharmaceutical development due to its role in the melanocortin system and related metabolic pathways. It is primarily utilized by research institutions, diagnostic manufacturers, and biopharmaceutical companies engaged in neuroscience, endocrinology, and peptide-based therapeutic discovery.

Application

• Biomedical Research: Used as a critical reference standard and reagent in studies investigating the POMC-derived peptide family, melanocortin receptors, and their physiological functions.
• Pharmaceutical R&D: Serves as a key intermediate or analytical standard in the development of novel therapeutics targeting obesity, metabolic disorders, and inflammatory conditions.
• Diagnostic Development: Employed in the calibration and validation of immunoassays (e.g., ELISA) designed to detect POMC-related peptides in clinical and research samples.
• Neuroscience Studies: Applied in research exploring the central nervous system's role in stress response, energy homeostasis, and pain modulation.
• Academic Research: A vital tool for universities and research laboratories conducting fundamental studies on peptide biochemistry, hormone processing, and signal transduction.

Basic Information

Item	Details
Product Name	Pro-Opiomelanocortin Human Joining Peptide(77-109)
CAS No.	124222-22-6
Molecular Formula	C164H256N44O48S2
Molecular Weight	3699.3 g/mol
Synonyms	POMC Joining Peptide (77-109); Human POMC (77-109); Proopiomelanocortin-derived Joining Peptide; JP (77-109); hPOMC(77-109); γ-MSH Precursor Fragment; Melanocortin Precursor Peptide; POMC (77-109)
EINECS	Contact for details

Quality Control

Our Pro-Opiomelanocortin Human Joining Peptide(77-109) is manufactured under stringent conditions to ensure the highest standards of purity and batch-to-batch consistency. Each lot undergoes comprehensive analytical characterization, including HPLC for purity assessment and mass spectrometry for identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications. We adhere to quality management systems suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake. For long-term storage, keep desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.