Description

2,6-Difluoro-3-Nitrobenzamide is a high-purity fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its core value lies in its role as a versatile building block for constructing complex molecules, particularly in the pharmaceutical and agrochemical sectors. This compound is essential for researchers and manufacturers developing active pharmaceutical ingredients (APIs), crop protection agents, and specialty fine chemicals, where the introduction of fluorine atoms and nitro/amide functionalities is critical for modulating biological activity and physicochemical properties.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, especially those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the difluoro-nitrobenzamide scaffold contributes to efficacy and environmental profile.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of specialty polymers, liquid crystals, and advanced organic electronic materials.
• Chemical Biology & Proteomics: Employed as a tagging or cross-linking reagent in biochemical assays and probe development due to its reactive nitro and amide groups.
• Dye & Pigment Intermediate: Acts as a starting material for synthesizing complex fluorinated dyes and pigments with enhanced lightfastness and color properties.

Basic Information

Product Name	2,6-Difluoro-3-Nitrobenzamide
CAS No.	124169-54-6
Molecular Formula	C7H4F2N2O3
Molecular Weight	202.12 g/mol
Synonyms	3-Nitro-2,6-difluorobenzamide; 2,6-Difluoro-3-nitrobenzamide; Benzamide, 2,6-difluoro-3-nitro-; 124169-54-6; AI3-52362; SCHEMBL2334221; DTXSID90672966; ZINC000005014753
EINECS	Contact for details

Quality Control

Our 2,6-Difluoro-3-Nitrobenzamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be conducted under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.