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1,2-Bis(10(2',4'-Hexadienoyloxy)Decanoyl)-Sn-Glycero-3-Phosphocholine CAS NO 124154-20-7


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CAS No.:124154-20-7

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,2-Bis(10(2',4'-Hexadienoyloxy)Decanoyl)-Sn-Glycero-3-Phosphocholine is a synthetic, structured phospholipid derivative, specifically a phosphatidylcholine analogue with conjugated dienoyl chains. This compound matters for its role as a key intermediate and functional component in advanced lipid research and formulation. It is primarily needed by researchers and manufacturers in the pharmaceutical and biotechnology sectors for developing liposomal drug delivery systems, membrane biophysics studies, and as a specialized raw material for diagnostic reagents.

Application

  • Liposomal Drug Delivery: A critical component for formulating specialized liposomes designed for targeted drug delivery, particularly for sensitive therapeutic agents.
  • Membrane Biophysics Research: Used as a model membrane lipid to study lipid bilayer properties, phase behavior, and membrane-protein interactions due to its specific acyl chain structure.
  • Diagnostic Reagents: Serves as a functional phospholipid in the production of diagnostic kits and assays, such as those for phospholipase activity or lipid metabolism.
  • Biomimetic Coatings: Employed in the development of biocompatible coatings and surfaces that mimic natural cell membranes for medical devices and implants.
  • Specialty Lipid Synthesis: Acts as a high-purity intermediate for the chemical synthesis of more complex, labeled, or functionalized phospholipids for research purposes.

Basic Information

Product Name 1,2-Bis(10(2',4'-Hexadienoyloxy)Decanoyl)-Sn-Glycero-3-Phosphocholine
CAS No. 124154-20-7
Molecular Formula C52H90NO12P
Molecular Weight 952.24 g/mol
Synonyms 1,2-Bis(10-(2',4'-Hexadienoyloxy)decanoyl)-sn-glycero-3-phosphocholine; PC(C10:0/C10:0(2',4'-Hexadienoyl)); Conjugated Dienoyl Phosphatidylcholine; 1,2-Di(10-(2,4-hexadienoyloxy)decanoyl)-sn-glycero-3-phosphocholine; Phosphatidylcholine, 1,2-bis[10-[(2E,4E)-2,4-hexadienoyloxy]decanoyl]-; (2R)-2,3-Bis({10-[(2E,4E)-hexa-2,4-dienoyloxy]decanoyl}oxy)propyl 2-(trimethylazaniumyl)ethyl phosphate
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Quality Control

Our 1,2-Bis(10(2',4'-Hexadienoyloxy)Decanoyl)-Sn-Glycero-3-Phosphocholine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, MS), to ensure it meets the high standards required for pharmaceutical research and development. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item Specification
Appearance White to off-white solid or waxy solid
Identification (HPLC/MS) Conforms
Purity (HPLC) ≥ 95.0%
Water Content (KF) ≤ 2.0%
Solvent Residue (GC) Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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