Description

Laminin S CAS NO 124148-86-3 is a synthetic peptide fragment derived from the laminin protein, a key component of the extracellular matrix. This compound is crucial for research and development in cell biology and biomaterials, as it mimics the cell-adhesive and signaling properties of native laminin. It is primarily needed by biotechnology firms, academic research institutions, and pharmaceutical companies engaged in studies of cell adhesion, tissue engineering, and regenerative medicine.

Application

• Cell Culture Substrate Coating: Used to coat tissue culture plates and scaffolds to promote the attachment, spreading, and differentiation of various cell types, including stem cells and neurons.
• Biomaterial Functionalization: Incorporated into hydrogels, polymers, and other biomaterials to create bioactive surfaces that guide cell behavior in tissue engineering applications.
• Neuroscience Research: Serves as a critical substrate for studying neurite outgrowth, axon guidance, and neural network formation in vitro.
• Angiogenesis Studies: Employed in research models to investigate the mechanisms of blood vessel formation and endothelial cell function.
• Drug Discovery Screening: Utilized in high-throughput assays to identify compounds that modulate cell-matrix interactions relevant to cancer metastasis and fibrosis.
• Diagnostic Development: Acts as a capture agent or standard in immunoassays and biosensors designed to detect specific cell-surface integrins or matrix components.

Basic Information

Product Name	Laminin S
CAS No.	124148-86-3
Molecular Formula	C34H59N11O10
Molecular Weight	765.9 g/mol
Synonyms	Laminin Pentapeptide; Laminin Peptide YIGSR; Tyr-Ile-Gly-Ser-Arg; YIGSR Peptide; Laminin-1 (929-933); Laminin Cell-Adhesion Peptide; CDPGYIGSR; Adhesion Peptide YIGSR
EINECS	Contact for details

Quality Control

Our Laminin S is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity verification and mass spectrometry for identity confirmation, to ensure it meets the high standards required for life science research. Certificates of Analysis (COA) detailing purity, endotoxin levels, and sterility (where applicable) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature in a desiccator before opening to prevent condensation and hydrolysis. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC & MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Analysis	Within ± 10% of theoretical
Water Content (KF)	≤ 5.0%
Endotoxin Level	< 10 EU/mg
Solubility	Soluble in water or aqueous buffer

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.