Description

iso-Atrial Natriuretic Peptide is a synthetic analog of the endogenous cardiac hormone, designed for enhanced stability and research utility. This compound is critical for investigating cardiovascular physiology, renal function, and natriuretic peptide receptor signaling pathways. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic developers focused on heart failure, hypertension, and related metabolic disorders.

Application

• Biomedical Research: Used as a stable reference standard in studies of natriuretic peptide systems, receptor binding assays, and signal transduction mechanisms.
• Pharmaceutical Development: Serves as a key pharmacodynamic agent in preclinical models for cardiovascular and renal drug discovery programs.
• Diagnostic Assay Calibration: Employed in the development and quality control of immunoassays (e.g., ELISA) for detecting ANP-related biomarkers.
• Physiological Studies: Applied in experimental models to study blood pressure regulation, sodium excretion, and vascular tone.
• Academic & Clinical Research: Supports fundamental and translational research into heart failure, hypertension, and fluid-electrolyte balance.

Basic Information

Product Name	iso-Atrial Natriuretic Peptide
CAS No.	124147-23-5
Molecular Formula	C127H205N41O39S4
Molecular Weight	Approx. 2850.4 g/mol
Synonyms	iso-ANP; Atriopeptin analog; ANP (1-28), iso-; Human Atrial Natriuretic Factor analog; Cardionatrin I analog; Auriculin A analog; ANF analog; Atrial Natriuretic Peptide isomer
EINECS	Contact for details

Quality Control

Our iso-Atrial Natriuretic Peptide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and stringent controls for endotoxin and moisture content. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccant and under an inert atmosphere. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Peptide Content	≥ 80.0% (by amino acid analysis)
Water Content (KF)	≤ 5.0%
Acetate Content (HPLC)	≤ 10.0%
Single Impurity (HPLC)	≤ 2.0%
Endotoxin	< 10 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.