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Abaecin CAS NO 123997-18-2
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CAS No.:123997-18-2
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Abaecin CAS NO 123997-18-2 is a cationic antimicrobial peptide (AMP) originally isolated from the honey bee, *Apis mellifera*. This compound is of significant interest due to its potent activity against a broad spectrum of Gram-positive bacteria, including antibiotic-resistant strains. It serves as a valuable research tool for studying innate immunity and developing novel therapeutic agents in the pharmaceutical and biotechnology sectors.
Application
- Biomedical Research: Used as a reference standard and active agent in studies of antimicrobial peptides, host-pathogen interactions, and innate immune system mechanisms.
- Pharmaceutical Development: Investigated as a lead compound for the development of new anti-infective drugs, particularly against drug-resistant bacterial infections.
- Veterinary Science: Explored for potential applications in animal health, given its natural origin in bees and activity against pathogens affecting livestock.
- Cosmeceuticals: Evaluated for incorporation into topical formulations for its antimicrobial properties in skin care products.
- Biotechnology: Serves as a model peptide in structural biology studies and for engineering novel peptides with enhanced stability or activity.
- Agricultural Research: Studied for potential use in plant protection strategies as a natural biocontrol agent against bacterial phytopathogens.
Basic Information
| Product Name | Abaecin |
| CAS No. | 123997-18-2 |
| Molecular Formula | C92H147N31O26 |
| Molecular Weight | 2024.3 g/mol |
| Synonyms | Abaecin (Apis mellifera); Honeybee Abaecin; Antimicrobial Peptide Abaecin; Apidaecin-Type Peptide; Bee-derived Antibacterial Peptide; Innate Immunity Peptide Abaecin; GNNRPVYIPQPRPPHPRL |
| EINECS | Contact for details |
Quality Control
Our Abaecin is produced and analyzed under strict quality management protocols. Each batch undergoes comprehensive testing including HPLC for purity determination, mass spectrometry (MS) for identity confirmation, and endotoxin level analysis to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are available upon request.
Storage
Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store under desiccant. Allow the vial to warm to room temperature before opening to minimize moisture absorption.
Specification
| Item | Specification |
|---|---|
| Appearance | White to off-white lyophilized powder |
| Identification (HPLC & MS) | Conforms to reference standard |
| Purity (HPLC) | ≥ 95% |
| Peptide Content | ≥ 80% (by weight) |
| Water Content (KF) | ≤ 5.0% |
| Endotoxin Level | < 10 EU/mg |
| Solubility | Soluble in water, dilute acetic acid |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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