Description

3-(4-Methoxyspiro(1,2-Dioxetane-3,2'-Tricyclo(3.3.1.1(3,7))Decan)-4-Yl)Phenylgalactopyranoside is a highly specialized chemiluminescent substrate, specifically engineered for sensitive detection applications. Its core value lies in its ability to generate a strong, sustained light signal upon enzymatic cleavage, making it a critical reagent for advanced analytical assays. This compound is essential for researchers and manufacturers in the fields of molecular diagnostics, immunoassay development, and high-throughput screening. The product is supplied with CAS No. 123954-01-8.

Application

• Chemiluminescent Immunoassays (CLIA): As a substrate for β-galactosidase or other hydrolase enzyme labels in clinical diagnostic kits for hormones, tumor markers, and infectious diseases.
• Molecular Biology Research: Detection of reporter gene expression (e.g., lacZ) in cellular and molecular biology studies.
• Biosensor Development: Integration into sensor platforms for the ultrasensitive detection of pathogens, toxins, or specific analytes.
• High-Throughput Screening (HTS): Used in pharmaceutical and biotechnology research for enzyme inhibitor or activator assays.
• DNA Probe Assays: Employed in hybridization assays where enzyme-labeled probes require a highly sensitive detection method.
• Quality Control in Biologics: Monitoring enzymatic activity or contamination in biomanufacturing processes.

Basic Information

Product Name	3-(4-Methoxyspiro(1,2-Dioxetane-3,2'-Tricyclo(3.3.1.1(3,7))Decan)-4-Yl)Phenylgalactopyranoside
CAS No.	123954-01-8
Molecular Formula	C25H32O9
Molecular Weight	476.52 g/mol
Synonyms	Galacton-Plus; 3-(4-Methoxyspiro[1,2-dioxetane-3,2'-tricyclo[3.3.1.13,7]decan]-4-yl)phenyl β-D-galactopyranoside; Chemiluminescent Galactoside Substrate; β-Galactosidase Chemiluminescent Substrate; AMPGD (Analog); Dioxetane Galactoside; Lumigen PS-3 (related trade name); 4-Methoxy-4-(3-β-galactopyranosyloxyphenyl)spiro(adamantane-2,3'-[1,2]dioxetane)
EINECS	Contact for details

Quality Control

Every batch of our chemiluminescent substrate is produced and tested under strict quality management systems to ensure exceptional performance and lot-to-lot consistency. We provide comprehensive Certificates of Analysis (COA) that detail purity, functional performance in standard assays, and absence of interfering impurities. Our quality protocols are designed to meet the rigorous demands of in-vitro diagnostic (IVD) and research reagent manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This compound is strictly light-sensitive and hygroscopic; prolonged exposure to light, moisture, or elevated temperatures will lead to decomposition and loss of activity. Allow the vial to equilibrate to room temperature in a dark place before opening to minimize condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Specific Activity (Chemiluminescence)	Reported per COA
Solubility	Soluble in DMSO, DMF; slightly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.