Description

Pro-Opiomelanocortin Joining Peptide(77-97) is a defined synthetic peptide fragment corresponding to the joining region of the pro-opiomelanocortin (POMC) precursor protein. This high-purity reference standard is critical for research into neuroendocrine signaling, peptide hormone processing, and the regulation of the hypothalamic-pituitary-adrenal axis. It is primarily utilized by pharmaceutical R&D teams, academic research institutions, and diagnostic manufacturers focused on endocrinology, neuroscience, and metabolic disorders.

Application

• Biomedical Research: Used as a reference standard in studies investigating the biosynthesis and post-translational processing of POMC-derived hormones like ACTH, β-endorphin, and MSH.
• Assay Development: Serves as a critical antigen or calibrator in the development of immunoassays (ELISA, RIA) for detecting POMC-related peptides in biological samples.
• Neuroendocrine Studies: Applied in physiological and pharmacological research to understand the role of the joining peptide in hormone regulation and stress response pathways.
• Pharmaceutical Screening: Utilized in target validation and screening platforms for drug discovery programs aimed at modulating the melanocortin system or related metabolic disorders.
• Quality Control: Acts as a system suitability standard in the analytical quality control of related peptide-based pharmaceuticals or diagnostic kits.

Basic Information

Product Name	Pro-Opiomelanocortin Joining Peptide(77-97)
CAS No.	123723-76-2
Molecular Formula	C115H179N33O34S
Molecular Weight	2555.9 g/mol
Synonyms	POMC Joining Peptide (77-97); Human POMC (77-97); Proopiomelanocortin Joining Peptide Fragment 77-97; POMC(77-97); hPOMC(77-97); JP; Joining Region Peptide; Pro-opiomelanocortin-derived joining peptide
EINECS	Contact for details

Quality Control

Every batch of Pro-Opiomelanocortin Joining Peptide(77-97) is manufactured under controlled conditions and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our quality commitment includes comprehensive characterization by HPLC, MS, and amino acid analysis. A Certificate of Analysis (COA) detailing purity, peptide content, and analytical results is provided with each shipment to support your research and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to store desiccated. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80%
Amino Acid Composition	Conforms to theoretical values (±10%)
Single Impurity (HPLC)	≤ 1.0%
Water Content (KF)	≤ 5.0%
Solubility	Soluble in water or dilute acetic acid

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.