Description

Insulin-Like Growth Factor I (57-70) is a specific, bioactive peptide fragment derived from the C-terminal region of the Insulin-like Growth Factor I (IGF-I) protein. This compound is of significant value for research into the structure-activity relationships and biological functions of IGF-I, a key regulator of cell growth, differentiation, and metabolism. It is primarily needed by biotechnology and pharmaceutical research laboratories for use in biochemical studies, assay development, and as a reference standard.

Application

• Biochemical Research: Used as a critical tool for studying the binding interactions and signaling mechanisms of the IGF-I receptor.
• Assay Development: Serves as a reference standard or competitive ligand in ELISA, RIA, and other bioanalytical assays targeting IGF-I activity.
• Structure-Activity Relationship (SAR) Studies: Essential for mapping the bioactive regions of the full-length IGF-I protein to understand its function.
• Pharmaceutical R&D: Employed in the discovery and screening of potential therapeutic agents that modulate the IGF-I pathway.
• Cell Culture Studies: May be used to investigate the effects of specific IGF-I domains on cell proliferation and differentiation in vitro.

Basic Information

Product Name	Insulin-Like Growth Factor I (57-70)
CAS No.	123618-03-1
Molecular Formula	C70H111N19O21
Molecular Weight	1514.76 g/mol
Synonyms	IGF-I (57-70); IGF-I C-terminal fragment (57-70); Somatomedin C (57-70); Insulin-like growth factor I fragment 57-70; H-Tyr-Arg-Ser-Arg-Arg-Ser-Ser-Ser-Arg-Arg-Arg-Glu-Gly-OH; TRSRRSSSRRREGG; CAS 123618-03-1
EINECS	Contact for details

Quality Control

Our Insulin-Like Growth Factor I (57-70) is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing, including reversed-phase HPLC for purity assessment and mass spectrometry (MS) for identity confirmation. A Certificate of Analysis (COA) detailing purity, identity, and other relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Peptide Content	≥ 80% (by weight)
Water Content (KF)	≤ 5.0%
Acetate Content (HPIC)	≤ 10.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.