Description

Fibroblast Growth Factor-4 Human Recombinant (FGF-4) is a high-purity, biologically active protein produced using recombinant DNA technology. This growth factor plays a critical role in cellular signaling, promoting the proliferation and differentiation of a wide range of mesoderm- and neuroectoderm-derived cells. It is an essential reagent for advanced life science research, stem cell culture, and biopharmaceutical development. Key industries that rely on this product include biotechnology, academic research, and regenerative medicine.

Application

• Stem Cell Research & Culture: Used to maintain pluripotency and direct the differentiation of embryonic stem cells (ESCs) and induced pluripotent stem cells (iPSCs).
• Developmental Biology Studies: Investigates the role of FGF signaling in limb development, cardiogenesis, and other embryonic processes.
• Tissue Engineering & Regenerative Medicine: Incorporated into scaffolds and media formulations to promote tissue regeneration and wound healing models.
• Cancer Research: Studied for its involvement in angiogenesis, tumor growth, and metastasis in various cancer cell lines.
• Biopharmaceutical Production: Serves as a critical culture supplement for the expansion of specialized cell lines used in therapeutic protein manufacturing.
• Biochemical Assay Development: Utilized as a standard or active component in high-throughput screening (HTS) and receptor-binding studies.

Basic Information

Product Name	Fibroblast Growth Factor-4 Human Recombinant
CAS No.	123584-45-2
Molecular Formula	C770H1218N212O224S8
Molecular Weight	Approx. 17.8 kDa
Synonyms	FGF-4; Heparin Secretory Transforming Protein 1; HST-1; Heparin-Binding Growth Factor 4; HBGF-4; K-FGF; Kaposi Sarcoma Oncogene Homolog; FGF4; Recombinant Human FGF-4; Fibroblast Growth Factor Basic 4; Transforming Protein KS3
EINECS	Contact for details

Quality Control

Our recombinant Fibroblast Growth Factor-4 is manufactured under strict quality systems. Each lot is subjected to a comprehensive battery of tests to ensure identity, purity, potency, and consistency. Specifications meet the stringent requirements for research-grade biologics. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity by SDS-PAGE and HPLC, endotoxin level, biological activity via cell-based assays, and sterility.

Storage

Preserve in a tightly closed container, protected from light. For long-term storage, keep lyophilized powder at -20°C or below. Reconstituted solutions should be aliquoted and stored at -20°C to -80°C to avoid repeated freeze-thaw cycles. The product is hygroscopic (moisture-sensitive); ensure the vial is at room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White or off-white lyophilized powder
Identification (SDS-PAGE)	Single band, ~18-22 kDa
Purity (HPLC)	≥ 95%
Biological Activity	ED50 ≤ 2.0 ng/mL (Cell proliferation assay)
Endotoxin Level	< 1.0 EU/μg
Sterility (Membrane Filtration)	Sterile
Protein Content (UV Spectroscopy)	≥ 90% of label claim
Solubility	Soluble in water or PBS

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.