Description

δ2-Cefuroxime Axetil is a key pharmaceutical intermediate and the active isomer of the second-generation cephalosporin antibiotic, cefuroxime axetil. This compound is critical for ensuring the efficacy and purity of the final antibiotic formulation, which is used to treat a wide range of bacterial infections. It is primarily required by manufacturers in the pharmaceutical and fine chemical sectors for the synthesis of high-grade antibiotic products.

Application

• Active Pharmaceutical Ingredient (API) Intermediate: Primary use in the synthesis of cefuroxime axetil antibiotic formulations.
• Pharmaceutical Research & Development: Serves as a critical reference standard and starting material in antimicrobial drug discovery.
• Generic Drug Manufacturing: Essential for producing cost-effective, bioequivalent versions of cephalosporin antibiotics.
• Veterinary Medicine: Used in the development of antibacterial treatments for animals.
• High-Purity Chemical Synthesis: Employed in fine chemical synthesis where specific isomeric purity is required.

Basic Information

Product Name	δ2-Cefuroxime Axetil
CAS No.	123458-61-7
Molecular Formula	C20H22N4O10S
Molecular Weight	510.48 g/mol
Synonyms	(1RS)-1-[(Acetyloxy)ethyl] (6R,7R)-3-[(carbamoyloxy)methyl]-7-[[(Z)-2-furan-2-yl-2-(methoxyimino)acetyl]amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate; Cefuroxime Axetil Isomer; (Z)-Cefuroxime Axetil; δ2 Isomer of Cefuroxime Axetil; Cefuroxime 1-Acetoxyethyl Ester; Ceftin Intermediate; Zinnat Intermediate; CXM-AX
EINECS	Contact for details

Quality Control

Our δ2-Cefuroxime Axetil is manufactured under strict quality systems to meet the exacting standards of the pharmaceutical industry. Each batch is tested to ensure high isomeric purity and compliance with relevant pharmacopeial guidelines. A comprehensive Certificate of Analysis (COA) documenting identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
δ2-Isomer Purity	≥ 99.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.