Description

Pyrrolidine, 2-(1-Methylethyl)-1-(1-Oxo-2-Propenyl)-, (S)- (9Ci) CAS NO 123445-42-1 is a high-purity, chiral pyrrolidine derivative characterized by its unique isopropyl and acryloyl substituents. This compound serves as a versatile and critical chiral building block in advanced organic synthesis, enabling the creation of complex molecules with defined stereochemistry. It is primarily needed by pharmaceutical research and fine chemical manufacturers for developing active pharmaceutical ingredients (APIs), agrochemicals, and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Asymmetric Catalysis: Used as a precursor or ligand in the development of chiral catalysts for enantioselective synthesis.
• Agrochemical Synthesis: Employed in the production of advanced, stereochemically-defined pesticides and herbicides.
• Material Science Research: Acts as a monomer or functionalizing agent in the development of specialized polymers and advanced materials.
• Academic & R&D: A valuable reagent for methodological studies in organic chemistry and medicinal chemistry research laboratories.
• Peptidomimetics: Used in the design and synthesis of peptide analogs and conformationally restricted scaffolds for biological evaluation.

Basic Information

Product Name	Pyrrolidine, 2-(1-Methylethyl)-1-(1-Oxo-2-Propenyl)-, (S)- (9Ci)
CAS No.	123445-42-1
Molecular Formula	C10H17NO2
Molecular Weight	183.25 g/mol
Synonyms	(S)-1-Acryloyl-2-isopropylpyrrolidine; (S)-2-Isopropyl-1-(prop-2-enoyl)pyrrolidine; 1-(1-Oxo-2-propenyl)-2-(1-methylethyl)-(S)-pyrrolidine; L-1-Acryloyl-2-isopropylpyrrolidine; (S)-N-Acryloyl-2-isopropylpyrrolidine; 2-Isopropyl-1-acryloylpyrrolidine, (S)-; (S)-N-Acryloyl-2-(propan-2-yl)pyrrolidine
EINECS	Contact for details

Quality Control

Our production of Pyrrolidine, 2-(1-Methylethyl)-1-(1-Oxo-2-Propenyl)-, (S)- (9Ci) adheres to stringent quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure consistent high purity and enantiomeric excess (ee) suitable for sensitive synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for each shipment, supporting compliance in regulated environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Enantiomeric Excess)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.