Description

Boc-D-Asp(Ofm)-OH is a protected, non-natural amino acid derivative of significant importance in advanced organic synthesis. This high-purity building block is engineered to provide precise stereochemical control and selective reactivity, which is critical for constructing complex peptide architectures. It is primarily utilized by research institutions and pharmaceutical developers engaged in the synthesis of novel peptides, peptidomimetics, and bioactive compounds where the integrity of the aspartic acid side chain must be preserved.

Application

• Solid-Phase Peptide Synthesis (SPPS): A key protected intermediate for the controlled incorporation of D-aspartic acid into peptide chains.
• Pharmaceutical Research & Development: Used in the discovery and synthesis of potential therapeutic peptides, including hormone analogs and enzyme inhibitors.
• Peptidomimetic Design: Serves as a crucial scaffold for creating stable, drug-like molecules that mimic natural peptides.
• Bioconjugation & Labeling: The reactive carboxylic acid group, when deprotected, can be used for coupling with other molecules, tags, or solid supports.
• Chemical Biology Probes: Employed in the synthesis of labeled or modified peptides for studying biological pathways and protein interactions.
• Academic & Industrial Research: A fundamental reagent for methodological development in organic chemistry and peptide science.

Basic Information

Product Name	Boc-D-Asp(Ofm)-OH
CAS No.	123417-19-6
Molecular Formula	C15H16F3NO7
Molecular Weight	379.29 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-D-aspartic acid β-(9-fluorenylmethyl) ester; Boc-D-Aspartic acid 9-fluorenylmethyl ester; Boc-D-Asp(O-Fm)-OH;
EINECS	Contact for details

Quality Control

Our Boc-D-Asp(Ofm)-OH is manufactured under strict quality control protocols to ensure high chemical purity and consistent performance. Each batch is analyzed using advanced chromatographic and spectroscopic techniques, including HPLC, NMR, and mass spectrometry, to confirm identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.