Description

Vasopressin, 1-Deamino-(8-Lysine(N(6)-Tetramethylrhodamylaminothiocarbonyl))- is a chemically modified, fluorescently labeled analog of the neurohypophysial hormone vasopressin. This specialized derivative is engineered for advanced research applications, offering a powerful tool for visualization and tracking. It is primarily utilized by research scientists and pharmaceutical developers in the fields of neurobiology, receptor pharmacology, and diagnostic assay development. The compound's unique label enables precise study of vasopressin receptor binding, localization, and internalization dynamics.

Application

• Receptor Binding and Localization Studies: Fluorescent visualization of V1a and V2 vasopressin receptors in cellular and tissue models.
• Pharmacological Research: High-throughput screening and characterization of vasopressin receptor agonists and antagonists.
• Cellular Imaging and Trafficking: Real-time tracking of receptor-ligand complex internalization and intracellular pathways.
• Diagnostic Assay Development: Key component in developing fluorescence-based immunoassays or biosensors for vasopressin pathway analysis.
• Neuroscience and Physiology Research: Investigation of the role of vasopressin in central nervous system functions, social behavior, and fluid homeostasis.
• Bioconjugation and Probe Synthesis: Serves as a sophisticated starting material or reference standard for creating further diagnostic or research tools.

Basic Information

Product Name	Vasopressin, 1-Deamino-(8-Lysine(N(6)-Tetramethylrhodamylaminothiocarbonyl))-
CAS No.	123298-17-9
Molecular Formula	C72H105N19O16S2
Molecular Weight	1564.9 g/mol (approx.)
Synonyms	[Lys8(TMRITC)]-dAVP; 1-Deamino-8-Lysine(TMRITC)-vasopressin; TMRITC-Lys8-dAVP; Fluorescent Vasopressin Analog; Tetramethylrhodamine-Labeled Desmopressin Analog; TAMRA-Lys8-dAVP; Rhodamine-conjugated Vasopressin; d[D-Arg8, Lys(TMRITC)]-Vasopressin
EINECS	Contact for details

Quality Control

This high-purity biochemical is manufactured under controlled conditions to ensure batch-to-batch consistency for critical research. Rigorous quality testing is performed, including HPLC for purity and MS for identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and fluorescence properties is provided with each batch to support your research documentation and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store desiccated at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	Red to purple solid
Identification (HPLC/MS)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Absorption Maximum (λmax)	~550 nm
Emission Maximum (λem)	~575 nm
Water Content (KF)	≤ 5.0 %
Solubility	Soluble in DMSO, DMF; sparingly soluble in aqueous buffers

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.