Description

2-Amino-6-Iodobenzonitrile is a versatile halogenated aromatic nitrile building block of significant importance in advanced organic synthesis. Its molecular structure, featuring both an amino and an iodo substituent on the benzonitrile core, makes it a critical intermediate for constructing complex molecules. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Material Science: Serves as a building block for organic semiconductors, liquid crystals, and advanced polymers due to its electron-withdrawing nitrile group and potential for cross-coupling reactions.
• Chemical Synthesis: Employed in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) where the iodine atom acts as an excellent leaving group for carbon-carbon bond formation.
• Dye and Pigment Industry: Functions as an intermediate in the synthesis of specialized dyes and pigments requiring halogenated aniline derivatives.
• Academic & R&D: Utilized in university and corporate research laboratories for method development and exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	2-Amino-6-Iodobenzonitrile
CAS No.	123241-50-9
Molecular Formula	C7H5IN2
Molecular Weight	244.03 g/mol
Synonyms	6-Iodo-2-aminobenzonitrile; 2-Amino-6-iodobenzene carbonitrile; 2-Cyano-3-iodoaniline; Benzonitrile, 2-amino-6-iodo-; 3-Iodo-2-aminobenzonitrile; 2-Amino-6-iodo-benzonitrile; 6-Iodoanthranilonitrile
EINECS	Contact for details

Quality Control

Our 2-Amino-6-Iodobenzonitrile is manufactured under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.