Description

Achromopeptidase is a highly specific proteolytic enzyme derived from microbial sources, recognized for its ability to lyse bacterial cell walls without damaging mammalian cells. This property makes it an invaluable tool for the preparation of high-quality, intact DNA and RNA from a wide range of Gram-positive bacteria. It is essential for researchers and manufacturers in the life sciences and pharmaceutical industries who require reliable and efficient cell lysis for molecular biology, diagnostics, and bioprocessing applications.

Application

• Molecular Biology Research: Critical for the gentle lysis of Gram-positive bacteria (e.g., *Staphylococcus*, *Streptococcus*, *Bacillus*) to extract intact genomic DNA and RNA for PCR, sequencing, and cloning.
• Diagnostic Kit Manufacturing: Used as a key component in nucleic acid extraction kits and automated sample preparation systems for clinical and food safety testing.
• Pharmaceutical Development: Employed in the isolation of plasmids, chromosomes, and other cellular components from bacterial cultures during drug discovery and vaccine production.
• Microbiome and Metagenomic Studies: Facilitates the efficient breakdown of tough bacterial cell walls in complex samples, enabling comprehensive genetic analysis of microbial communities.
• Bioprocessing and Fermentation: Aids in the downstream processing of recombinant proteins and other products expressed in bacterial systems by lysing host cells.

Basic Information

Product Name	Achromopeptidase
CAS No.	123175-82-6
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Achromopeptidase; Achromobacter protease I; Lysyl endopeptidase; Achromopeptidase from *Achromobacter lyticus*; Bacterial cell wall lytic enzyme; M-lytic protease; API
EINECS	Contact for details

Quality Control

Our Achromopeptidase is produced and tested under strict quality management systems to ensure high purity, consistent activity, and reliable performance. Each batch is characterized for specific enzymatic activity, protein content, and absence of contaminating nucleases and proteases. Certificates of Analysis (COA) detailing purity, activity units/mg, and stability data are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. This product is hygroscopic (moisture-sensitive). For long-term stability, desiccate at -20°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (IR)	Conforms to standard
Protein Content (Biuret)	≥ 90%
Specific Activity	≥ 20,000 U/mg protein
DNase & RNase Activity	Not detected
Solubility	Clear, colorless solution in buffer or water
pH (1% solution)	6.0 - 8.0

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.