Description

Cefepime Hydrochloride is a fourth-generation, broad-spectrum cephalosporin antibiotic. This compound is valued for its enhanced stability against β-lactamases and potent activity against a wide range of Gram-positive and Gram-negative bacteria. It is a critical active pharmaceutical ingredient (API) primarily required by pharmaceutical manufacturers for the formulation of injectable antibiotic drugs. Its efficacy makes it essential for treating serious hospital-acquired infections, including pneumonia, bacteremia, and febrile neutropenia.

Application

• Pharmaceutical API: Primary use as the active ingredient in sterile injectable formulations (powder for solution).
• Hospital Infection Treatment: Formulated into drugs for combating complicated intra-abdominal infections, urinary tract infections (UTI), and skin structure infections.
• Empirical Therapy: Used in drug formulations for initial, broad-spectrum treatment of severe infections before specific pathogens are identified.
• Pediatric and Adult Formulations: Serves as a key component in antibiotic preparations for various patient demographics.
• Research & Development: Utilized in microbiological studies, stability testing, and the development of new combination therapies or dosage forms.
• Reference Standard: High-purity grades are used as analytical standards in quality control laboratories for drug testing and verification.

Basic Information

Product Name	Cefepime Hydrochloride
CAS No.	123171-59-5
Molecular Formula	C19H25ClN6O5S2 • HCl
Molecular Weight	571.94 g/mol (for Cefepime Hydrochloride)
Synonyms	Cefepime HCl; Cefepime Hydrochloride Monohydrate (common form); (6R,7R)-7-[[(2Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-methoxyiminoacetyl]amino]-3-(1-methylpyrrolidin-1-ium-1-yl)methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride; BMY-28142 hydrochloride; Axepim; Maxipime (Brand Name); Cefepime Dihydrochloride (less common)
EINECS	Contact for details

Quality Control

Our Cefepime Hydrochloride is manufactured and tested under strict quality management systems. It is produced to meet high-purity standards suitable for pharmaceutical applications, with potential alignment to pharmacopeial monographs (e.g., USP, EP). Every batch undergoes comprehensive analytical testing including assay, impurity profile, and microbiological examination. A Certificate of Analysis (COA) documenting all test results is provided to ensure full traceability and compliance with your quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
pH (1% Solution)	3.5 - 5.5
Water Content (KF)	≤ 1.5%
Residue on Ignition	≤ 0.2%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any individual impurity ≤ 1.0%
Bacterial Endotoxins	< 0.05 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.