Description

Boc-L-2-Amino-5-Methylhex-4-Enoic Acid is a protected amino acid derivative featuring a unique unsaturated side chain, making it a valuable non-proteinogenic building block for peptide synthesis and medicinal chemistry research. Its primary value lies in enabling the introduction of structural complexity and specific functionalities into synthetic peptides and peptidomimetics, which are crucial for developing novel bioactive compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical sectors who require high-purity, specialized amino acids for advanced R&D and process development.

Application

• Pharmaceutical Intermediate: A key building block in the solid-phase and solution-phase synthesis of novel therapeutic peptides and peptidomimetics.
• Medicinal Chemistry Research: Used to incorporate the unique 2-amino-5-methylhex-4-enoic acid moiety into lead compounds for structure-activity relationship (SAR) studies.
• Bioconjugation & Probe Development: Serves as a precursor for creating labeled peptides or affinity probes due to its reactive amine group (after deprotection) and olefin handle for further modification.
• Agrochemical Research: Employed in the synthesis of peptide-based or amino acid-derived bioactive agents for crop protection.
• Academic & Institutional R&D: Utilized in university and research institute laboratories for studying peptide structure, function, and developing new synthetic methodologies.

Basic Information

Product Name	Boc-L-2-Amino-5-Methylhex-4-Enoic Acid
CAS No.	123098-61-3
Molecular Formula	C₁₂H₂₁NO₄
Molecular Weight	243.30 g/mol
Synonyms	N-(tert-Butoxycarbonyl)-L-2-amino-5-methyl-4-hexenoic acid; Boc-AHMA-OH; (2S)-2-[(tert-Butoxycarbonyl)amino]-5-methylhex-4-enoic acid; Boc-L-2-Amino-5-methyl-4-hexenoic Acid; N-Boc-L-2-Amino-5-methyl-4-hexenoic acid; tert-Butyl (1S)-1-carboxy-4-methyl-3-pentenylcarbamate; Boc-Ahme-OH
EINECS	Contact for details

Quality Control

Our Boc-L-2-Amino-5-Methylhex-4-Enoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR), to ensure it meets the high standards required for research and development applications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with specified parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.