Description

Boc-n-Me-Ser-Ome CAS NO 122902-81-2 is a protected serine derivative, specifically the methyl ester of N-Boc-N-methyl-L-serine, serving as a crucial chiral building block in organic synthesis. This compound is essential for researchers and manufacturers requiring high-purity, structurally defined intermediates to ensure the fidelity of complex molecular assembly. It is primarily needed by pharmaceutical R&D teams and fine chemical producers engaged in the synthesis of peptides, peptidomimetics, and other bioactive molecules where precise stereochemistry and functional group protection are paramount.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly in oncology and metabolic disease research.
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis (SPPS) to incorporate N-methylated serine residues, which can enhance metabolic stability and alter conformational properties of therapeutic peptides.
• Prodrug Development: Serves as a precursor for constructing prodrug linkers or modifying drug molecules to improve solubility, bioavailability, or targeting.
• Chemical Biology Research: Employed in the synthesis of labeled compounds, molecular probes, and tools for studying enzyme mechanisms and protein-protein interactions.
• Asymmetric Synthesis: Utilized as a starting material or intermediate in catalytic asymmetric reactions to construct complex natural products and chiral compounds.
• Fine Chemical Production: Integral to the multi-step synthesis of specialty chemicals, agrochemicals, and advanced materials requiring protected amino acid frameworks.

Basic Information

Product Name	Boc-n-Me-Ser-Ome
CAS No.	122902-81-2
Molecular Formula	C10H19NO5
Molecular Weight	233.26 g/mol
Synonyms	(2S)-2-[(tert-Butoxycarbonyl)(methyl)amino]-3-hydroxypropanoic acid methyl ester; Methyl (2S)-2-[(tert-butoxycarbonyl)(methyl)amino]-3-hydroxypropanoate; N-Boc-N-methyl-L-serine methyl ester; Boc-N-Me-Ser-OMe; (S)-Methyl 2-((tert-butoxycarbonyl)(methyl)amino)-3-hydroxypropanoate; tert-Butyl ((2S)-3-hydroxy-1-methoxy-1-oxopropan-2-yl)(methyl)carbamate; Boc-N-methylserine methyl ester; L-Serine, N-[(1,1-dimethylethoxy)carbonyl]-N-methyl-, methyl ester
EINECS	Contact for details

Quality Control

Our Boc-n-Me-Ser-Ome is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification, to ensure compliance with high-purity standards for research and pharmaceutical applications. Certificates of Analysis (COA) detailing identity, purity (typically ≥98% by HPLC), and impurity profiles are available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation [α]	Contact for details
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.