Description

7Beta-Amino-3-[3-Amino-2-(2-Hydroxyethyl)-1-Pyrazolio]Methyl-3-Cephem-4-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate, specifically a cephalosporin nucleus derivative, essential for the synthesis of next-generation β-lactam antibiotics. Its primary value lies in enabling the development of potent antibacterial agents with enhanced efficacy and resistance profiles. This compound is critically needed by research institutions, fine chemical manufacturers, and pharmaceutical companies engaged in the development and production of novel cephalosporin-based therapeutics. The product, identified by CAS NO 122841-17-2, is supplied under stringent quality controls to ensure batch-to-batch consistency for demanding synthesis processes.

Application

• Key Intermediate for Antibiotic Synthesis: Serves as a crucial building block in the multi-step synthesis of advanced cephalosporin antibiotics.
• Pharmaceutical Research & Development (R&D): Used in medicinal chemistry for the discovery and structural modification of new antibacterial compounds.
• Active Pharmaceutical Ingredient (API) Manufacturing: Incorporated into the production process of final drug substances for clinical and commercial use.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes and scaling production from laboratory to pilot and commercial scales.
• Reference Standard: Utilized as a high-purity analytical standard for quality control and regulatory submissions in pharmaceutical manufacturing.

Basic Information

Product Name	7Beta-Amino-3-[3-Amino-2-(2-Hydroxyethyl)-1-Pyrazolio]Methyl-3-Cephem-4-Carboxylate Hydrochloride
CAS No.	122841-17-2
Molecular Formula	C13H20ClN6O4
Molecular Weight	359.79 g/mol
Synonyms	7β-Amino-3-[(3-amino-2-(2-hydroxyethyl)pyrazol-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride; (6R,7R)-7-Amino-3-[(3-amino-2-(2-hydroxyethyl)-1H-pyrazol-1-ium-1-yl)methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid chloride; Cephalosporin C-7 Nucleus Derivative; 7-ACA Pyrazolium Derivative HCl; 7β-Aminocephalosporanic Acid Pyrazolium Salt Hydrochloride; 122841-17-2 (CAS); 7-ADCA Intermediate
EINECS	Contact for details

Quality Control

Our 7Beta-Amino-3-[3-Amino-2-(2-Hydroxyethyl)-1-Pyrazolio]Methyl-3-Cephem-4-Carboxylate Hydrochloride is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and conformity to stringent specifications. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.