Description

Cefoselis Sulfate is a fourth-generation cephalosporin antibiotic, specifically formulated as the sulfate salt to enhance its stability and solubility for pharmaceutical manufacturing. This advanced antibiotic is valued for its broad-spectrum activity against a wide range of Gram-positive and Gram-negative bacteria, including resistant strains. It is a critical active pharmaceutical ingredient (API) primarily required by pharmaceutical companies and research institutions engaged in the development and production of injectable antibiotic formulations.

Application

• Primary Active Pharmaceutical Ingredient (API) in the formulation of sterile injectable antibiotic products.
• Research and development of novel antibacterial therapies and combination treatments.
• Manufacturing of bulk pharmaceutical preparations for hospital-use injectables.
• Reference standard in analytical laboratories for quality control and method development.
• Intermediate in the synthesis of more complex cephalosporin derivatives.
• Component in microbiological research for studying bacterial resistance mechanisms.

Basic Information

Product Name	Cefoselis Sulfate
CAS No.	122841-12-7
Molecular Formula	C20H22N8O8S2 • H2SO4
Molecular Weight	666.63 g/mol (for free base, contact for salt-specific weight)
Synonyms	Cefoselis Sulphate; FK-037; FR-21818; (6R,7R)-7-[(Z)-2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetamido]-3-[5-(1-methyl-1H-tetrazolium-5-yl)thiomethyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate sulfate; Cefoselis Sulfate Monohydrate (common form)
EINECS	Contact for details

Quality Control

Our Cefoselis Sulfate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide Certificates of Analysis (COA) detailing key parameters such as assay, impurities, and microbiological data. The product is developed with reference to relevant pharmacopeial guidelines to support our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
pH (in solution)	3.5 - 5.5
Bacterial Endotoxins	< 0.10 EU/mg
Sterility (for sterile grade)	Sterile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.